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The inhibition of heat shock protein 90 mediated by RGRN-305 serves as a potential therapeutic tool in the treatment of hidradenitis suppurativa, according to the results of a new clinical trial. Hidradenitis suppurativa (HS) is an immune-mediated systemic inflammatory condition, predominantly associated with cutaneous changes. Heat shock protein 90 (HSP90) mediates the activity of proinflammatory...

A new randomized clinical trial shows that pitavastatin or other statins may help reduce major cardiovascular events in those living with HIV. These benefits are not just due to LDL cholesterol reduction. HIV significantly increases atherosclerotic cardiovascular disease incidence in those living with HIV. Studies suggest that those living with HIV have twice the risk...

Patients with heart failure typically experience high rates of morbidity and mortality, as well as increased healthcare costs. Disparities in risk factors and treatment strategies for patients with heart failure exist and need to be addressed by the healthcare community. Disparities in heart failure risk factors and treatment methods span across racial and ethnic groups....

Heart disease is a terrifying medical issue that kills around 697,000 Americans each year. Because of this, preventing heart disease is a top issue for many.  However, the possibility of a genetic condition adds a hurdle to this. If heart disease is genetic, can it truly be managed?  This article will explore the genetic nature...

FRIDAY, Feb. 12, 2021  — The absolute numbers of heart failure prevalent cases and years lived with disability (YLD) increased from 1990 to 2017, according to a study published online Feb. 12 in the European Journal of Preventive Cardiology. Nicola Luigi Bragazzi, M.D., Ph.D., from Xiangya Hospital in Changsha, China, and colleagues collected data on...

From 1990, increase in absolute numbers of heart failure prevalent cases and years lived with disability The absolute numbers of heart failure prevalent cases and years lived with disability (YLD) increased from 1990 to 2017, according to a study published online Feb. 12 in the European Journal of Preventive Cardiology. Nicola Luigi Bragazzi, M.D., Ph.D., from...

Poor health literacy is associated with worse heart failure outcomes, according to a review published in the June issue of JACC: Heart Failure. Matteo Fabbri, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues conducted a systematic literature review to evaluate associations between health literacy and health-related outcomes in patients with heart failure. Based on...

By American Heart Association NewsHeart attack survivors who receive home health care are less likely to be readmitted to the hospital within the first month, according to preliminary research. The study, presented Friday at the American Heart Association’s Quality of Care & Outcomes Research Scientific Sessions, used the Nationwide Readmission Database to identify more than 400,000...

Here’s a sobering stat: heart disease is the No. 1 cause of death for men and women, according to the Centers for Disease Control and Prevention (CDC). The good news? You can take actionable steps to improve your heart health and lower your chances of developing heart disease. What is heart disease? Heart disease is an...

MONDAY, Nov. 16, 2020 (HealthDay News) — Adherence to healthy sleep patterns is associated with a lower risk for heart failure, according to a research letter published online Nov. 16 in Circulation. Xiang Li, Ph.D., from the School of Public Health and Tropical Medicine at Tulane University in New Orleans, and colleagues prospectively investigated the...