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The consumption of a low-fat, plant-based diet containing decreased dietary advanced glycation end-products aids in reducing the frequency of severe hot flashes in postmenopausal women.

Hot flashes in postmenopausal women tend to be associated with a greater risk of developing diabetes and cardiovascular diseases. Changes in the dietary consumption of advanced glycation end-products (AGEs) have beneficial effects on vasomotor symptoms in postmenopausal women. 

In this secondary analysis, the authors evaluated the relationship between dietary AGEs and changes in hot flashes in postmenopausal women. The study concluded that a reduction in the dietary intake of AGEs led to a significant decrease in the frequency of postmenopausal hot flashes. The findings are published in the journal Maturitas.

Study Characteristics

A total of 63 patients provided complete data for this post-hoc analysis. There were no significant differences in the baseline parameters of control group and intervention group participants.

Intake of Dietary Advanced Glycation End-Products

There was a 73% decrease in the dietary AGEs in the intervention group participants compared to a 7% increase recorded in the control group participants. The reduction in dietary AGEs is attributed to a decrease in dairy and meat intake. There was a significant association between changes in dietary AGEs and postmenopausal hot flashes. This association was not influenced by energy intake or body mass index changes.

Low-Fat Plant-Based Diet Reduces Severe Hot Flashes in Postmenopausal Women

The consumption of a low-fat plant-based diet containing decreased dietary AGEs aids in reducing the frequency of severe hot flashes in postmenopausal women. Hence, plant-based diets are effective in managing both vasomotor symptoms and reducing other AGE-mediated health risks.

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Kahleova, H., Znayenko-Miller, T., Uribarri, J., Schmidt, N., Kolipaka, S., Hata, E., Holtz, D. N., Sutton, M., Holubkov, R., & Barnard, N. D. (2023). Dietary advanced glycation end-products and postmenopausal hot flashes: A post-hoc analysis of a 12-week randomized clinical trial. Maturitas, 172, 32–38. https://doi.org/10.1016/j.maturitas.2023.03.008