Alzheimer’s Disease

Higher pancreatic fat linked to lower cognition and brain volumes in middle-aged men at high risk for Alzheimer disease Higher pancreatic fat percentage is associated with lower cognition and brain volumes in middle-aged men at high risk for Alzheimer disease, according to a study published online Feb. 27 in Obesity. Sapir Golan Shekhtman, from Tel Aviv...

Authors say future work should focus on determining if transfers are needed Patients with Alzheimer disease and other related dementias (ADRD) are less likely to receive intensive care unit admission or procedures after transfer from an emergency department to a tertiary care hospital, according to a study recently published in Alzheimer’s & Dementia: Diagnosis, Assessment &...

Younger age at a-fib onset linked to increased risks of all-cause and vascular dementia, Alzheimer disease   Earlier onset of atrial fibrillation (AF) is associated with increased risk of developing all-cause dementia, vascular dementia (VD), and Alzheimer disease (AD), according to a study published online Nov. 8 in JAMA Network Open. Wenya Zhang, from the Chinese...

Among patients with ADRD receiving care from a home health agency, antipsychotic use was tied to less improvement in activities of daily living. Antipsychotics are more often used by older adults receiving home health care (HHC) services with Alzheimer disease and related dementias (ADRD) versus those without ADRD, and their use is associated with worse...

As extreme heat continues to blanket numerous parts of the United States, Americans with dementia may be particularly challenged. “Triple-digit temperatures and heat indexes are especially dangerous for someone with a dementia-related illness such as Alzheimer’s disease, because the effects of dementia can impair their ability to notice if they are developing heat stroke or...

Change in gut microbiome composition associated with β-amyloid and tau pathological brain biomarkers. Gut microbial taxonomic profiles are distinct for individuals with and without preclinical Alzheimer disease (AD), according to a study published in the June 14 issue of Science Translational Medicine. Aura L. Ferreiro, Ph.D., from the Washington University School of Medicine in St. Louis,...

Greater effect seen for patients aged 70 years and older at time of bacillus Calmette-Guerin vaccination. The bacillus Calmette-Guerin (BCG) vaccine is associated with a significantly lower rate and risk for Alzheimer disease and related dementias (ADRD) among patients with bladder cancer, according to a study published online May 19 in JAMA Network Open. Marc S....

Allopurinol linked to 13 to 34 percent lower risk for Parkinson disease, Alzheimer disease, ALS Xanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 in PLOS ONE. Yizhe Song, from the Washington University School of Medicine in St. Louis, and colleagues conducted a population-based, case-control study...

Key Takeaways Memory loss is the most common early symptom of Alzheimer’s and dementia, but it doesn’t necessarily signal a rapid decline People whose earliest symptoms involve language, decision making or problem solving tend to have a faster and steeper decline in their brain function and quality of life, a new study found The results...