Patients with transthyretin amyloidosis cardiomyopathy (ATTR-CM) are at risk of cardiovascular comorbidities, including atrial fibrillation and flutter. Routine ambulatory monitoring in patients with ATTR-CM could help drive the use of anticoagulation to prevent strokes. Heart…
Daysha RobinsonSeptember 15, 2022
The awareness and diagnosis of wild‐type transthyretin amyloid cardiomyopathy (ATTRwt CM) is challenging, despite ATTRwt being more common than previously thought. Screening is necessary for early detection and diagnosis of ATTRwt CM, as well as…
Daysha RobinsonSeptember 15, 2022
Heart failure, among other cardiovascular problems, is a typical manifestation of transthyretin amyloidosis cardiomyopathy (ATTR-CM). The prevalence of ATTR-CM as a phenotype of heart failure is often underestimated. Heart failure with preserved ejection fraction (HFpEF)…
Daysha RobinsonSeptember 15, 2022
Medication adherence is a critical aspect of treating patients with ATTR-CM and ensuring optimal outcomes. Research suggests that many patients with ATTR-CM are adherent to treatment with tafamidis, partly due to the availability of a…
Daysha RobinsonSeptember 6, 2022
An early diagnosis of transthyretin amyloidosis (ATTR) is key for managing the disease and preventing costly complications. One study suggests that cardiovascular symptoms and increased hospitalizations are a potential way to identify the disease early.…
Daysha RobinsonSeptember 6, 2022
Patients with transthyretin amyloid cardiomyopathy (ATTR-CM) are faced with different possibilities for treating their symptoms and underlying disease. However, treatment options may vary depending on the severity of the disease, the cost of the treatment,…
Daysha RobinsonSeptember 2, 2022
Transthyretin (TTR) gene variants may increase the risk of heart failure and other cardiac complications. A specific TTR gene variant at position 122 (V142I) is particularly common among middle-aged Black patients. The TTR V142I variant…
Anisha RaoAugust 12, 2022
Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is a rare, age-related, debilitating disease. In particular, the wild-type (ATTRwt) is often diagnosed in older patients who also present symptoms of other comorbidities. One review, published in Frontiers in Cardiovascular…
Anisha RaoAugust 8, 2022
The number of older patients in the United States is expected to increase by 69% between 2020 and 2060. In addition, ethnic and racial groups are expected to become the racial majority within the next…
Anisha RaoAugust 8, 2022
Light chain (AL) amyloidosis develops from precursor plasma cells that produce clonal free light chains. These clonal free light chains can lead to the formation of fibril deposits in the heart tissue and disrupt the…
Anisha RaoAugust 7, 2022