Dermatology

 A recent Delphi survey facilitated the establishment of diagnostic criteria and differential diagnoses between urticarial vasculitis and chronic spontaneous urticaria patients presenting with recurring wheals.  Urticarial vasculitis (UV) is characterized by long-lasting wheals with or without angioedema and the histopathologic finding of leukocytoclastic vasculitis. Distinguishing UV from chronic spontaneous urticaria (CSU) can be challenging due...

In the phase 2b ARROYO trial, although blood eosinophils were almost completely depleted, benralizumab treatment did not show any therapeutic advantage compared to a placebo for the treatment of chronic spontaneous urticaria. Chronic spontaneous urticaria (CSU) involves a complex interplay of various cell types and molecular mechanisms, with mast cells traditionally considered the primary drivers....

Chronic spontaneous urticaria causes systemic microcirculatory changes, which VEGF may partly drive, according to the results of a cross-sectional, cohort study. Chronic spontaneous urticaria (CSU) is characterized by recurrent wheals and angioedema resulting from the activation of skin mast cells, often driven by autoimmunity through IgE and IgG autoantibodies. In this context, a cross-sectional, cohort...

Investigator Global Assessment of 0 or 1 occurred in significantly more patients receiving tacrolimus microemulsion versus placebo For scalp psoriasis, 0.1 percent tacrolimus microemulsion has good efficacy and safety, according to a study published online Feb. 12 in Dermatology and Therapy. Andreas Pinter, M.D., from the University Hospital Frankfurt in Germany, and colleagues conducted a multicenter,...

Studies show that quantitative and qualitative alterations in the skin population of C. Acnes is associated with higher atopic dermatitis risk, according to the results of a new literature review. Cutibacterium acnes plays an opportunistic role in acne vulgaris. However, it is also a commensal bacteria that plays an important role in maintaining skin health,...

by Roger Mosley A retrospective cohort study analyzing a large dataset found that atopic dermatitis is associated with a significant increase in the risk of various skin cancer types. Atopic dermatitis (AD) causes scaly, itchy patches and is relatively benign. Although its pathogenesis is not fully understood, it is known that disruption in skin barrier...

A recent case series reports significant symptom improvement in periorbital atopic dermatitis symptoms with the use of tacrolimus ointment, with minimal side effects. This approach marks a notable advancement in dermatological and ophthalmological care, offering a promising alternative to traditional steroid treatments. Tacrolimus ointment shows promising outcomes in treating periorbital atopic dermatitis with minimal adverse...

Hyperspectral imaging emerges as a potential tool in diagnosing erythema severity within atopic dermatitis, offering improved accuracy over traditional visual assessments. This innovative approach could improve objectivity and efficiency in skin inflammation evaluation. Hyperspectral imaging offers a detailed evaluation of erythema, surpassing traditional visual assessments. This study compared the efficacy of hyperspectral imaging against conventional...

Significant health literacy limitations may exist among atopic dermatitis patients, highlighting the need for tailored healthcare communication and support. A cross-sectional study associates limited health literacy with poorer health-related quality of life and older age, suggesting potential ways to improve patient care. Nearly one-third of atopic dermatitis patients exhibit limited health literacy, impacting their ability...