fbpx Skip to main content

The incidence of wet age-related macular generation (AMD) is rising rapidly amidst an aging population. However, despite its name, age is not the only risk factor associated with wet AMD.

Environmental factors such as smoking have been known to increase the risk of wet AMD. Given the correlation between smoking and low socioeconomic status, this retrospective cohort study sought to compare baseline disease severity, treatment completion, and treatment outcomes among patients with wet AMD based on area socioeconomic status and the distance from a patient’s home to their treatment center.

Researchers analyzed the data of 756 patients with wet AMD over the age of 50 who received treatment with aflibercept between May 2013 and Jan 2017. Socioeconomic status was determined by factors such as income, living environment, and barriers to housing and services. Data were also collected on the proximity of patients to their hospital.

Findings showed that a significantly higher proportion of patients in the quintile with the lowest socioeconomic status presented with more severe cases of wet AMD than their high socioeconomic status counterparts. This finding was made with a correlation of greater wet AMD severity at baseline and greater area deprivation.

Furthermore, it was found that patients with lower socioeconomic status were more likely to have delayed treatment completion. This relationship was reduced after adjusting for age, gender, and distance from the hospital. Hospital distance was not found to be associated with baseline disease severity, treatment completion, or treatment outcome. 

The findings of this study can be used to target patients of lower socioeconomic status earlier to help prevent wet AMD progression and promote treatment adherence. Support for early detection in these communities and subsidizing care could lead to more equitable treatment and consequently improved quality of life for this vulnerable population [1].

You May Also Like::  MicroRNA Possible Biomarker For Early AMD Detection


[1] More, P., Almuhtaseb, H., Smith, D., Fraser, S., & Lotery, A. J. (2019). Socio-economic status and outcomes for patients with age-related macular degeneration. Eye, 33(8), 1224–1231. https://doi.org/10.1038/s41433-019-0393-3

“Keeping up with the indications and adverse reactions to immune checkpoint inhibitors can be a full-time job. Cutaneous side effects occur in up to 45% of patients treated with ipilimumab and 34% of patients treated with nivolumab and pembrolizumab.” https://bit.ly/3FGtxtd

.@spfnomt: This month’s #DermWorld article “Estate planning 101” is especially important for young physicians to read. The long, all-consuming years between adolescence and physicianhood can become a blur...https://bit.ly/3FxOtCv

That’s a wrap #AAD2023! 5 days of soaking up knowledge from dermatologists on topics such as hidradenitis, melasma, & dietary triggers of common dermatoses.

I LOVED the #womenshealth focused sessions on vulvar dermatoses and pregnancy medication safety.


New approach uses microbiome to treat skin disease by repairing the injured microbiome that allowed inflammation to flare up in the first place, rather than reducing the inflammation after the fact. https://bit.ly/3Jt6H9v

Load More