fbpx Skip to main content

FRIDAY, March 26, 2021 (HealthDay News) — Spontaneous abortion is associated with an elevated risk for premature mortality, according to a study published online March 24 in The BMJ.

Yi-Xin Wang, Ph.D., from the Harvard T. H. Chan School of Public Health in Boston, and colleagues conducted a prospective cohort study among 101,681 ever gravid female nurses participating in the Nurses’ Health Study II to examine the association between spontaneous abortion and the risk for premature mortality before age 70 years.

The researchers recorded 2,936 premature deaths during 24 years of follow-up. Women with and without a history of spontaneous abortion had comparable crude all-cause mortality rates (1.24 per 1,000 person-years in both groups), but rates were higher for women experiencing three or more spontaneous abortions and for those reporting their first spontaneous abortion before age 24 years (1.47 and 1.69 per 1,000 person-years, respectively). The occurrence of spontaneous abortion was associated with a hazard ratio of 1.19 for premature mortality during follow-up, after adjustment for confounding factors and updated dietary and lifestyle factors. The association was stronger for recurrent spontaneous abortions (hazard ratios, 1.59, 1.23, and 1.16 for three or more, two, and one versus none, respectively) and for spontaneous abortions occurring early in a woman’s reproductive life (hazard ratios, 1.32, 1.16, and 1.12 for age ≤23, 24 to 29, and ≥30 years, respectively). In the evaluation of cause-specific premature mortality, the association of spontaneous abortion with premature death was strongest for deaths from cardiovascular disease (hazard ratio, 1.48).

“Our results suggest that spontaneous abortion could be an early marker of future health risk in women, including premature death,” the authors write.

Abstract/Full Text

You May Also Like::  ACA's Reach Surges With 200,000 New Signups, More States Involved

“Keeping up with the indications and adverse reactions to immune checkpoint inhibitors can be a full-time job. Cutaneous side effects occur in up to 45% of patients treated with ipilimumab and 34% of patients treated with nivolumab and pembrolizumab.” https://bit.ly/3FGtxtd

.@spfnomt: This month’s #DermWorld article “Estate planning 101” is especially important for young physicians to read. The long, all-consuming years between adolescence and physicianhood can become a blur...https://bit.ly/3FxOtCv

That’s a wrap #AAD2023! 5 days of soaking up knowledge from dermatologists on topics such as hidradenitis, melasma, & dietary triggers of common dermatoses.

I LOVED the #womenshealth focused sessions on vulvar dermatoses and pregnancy medication safety.

#dermtwitter
@AADmember

New approach uses microbiome to treat skin disease by repairing the injured microbiome that allowed inflammation to flare up in the first place, rather than reducing the inflammation after the fact. https://bit.ly/3Jt6H9v

Load More