December 11, 2020

ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD

THURSDAY, Dec. 10, 2020 (HealthDay News) — Use of the ex vivo CRISPR-Cas9-based gene-editing platform to edit the erythroid enhancer region of BCL11A in hematopoietic stem and progenitor cells, producing CTX001, results in increased hemoglobin (Hb) among patients with transfusion-dependent ß-thalassemia (TDT) and sickle cell disease (SCD), according to a study published online Dec. 5...

Peripheral Neuropathy Linked to Mortality in U.S. Population

FRIDAY, Dec. 11, 2020 (HealthDay News) — Peripheral neuropathy (PN) is associated with mortality, even among individuals without diabetes, according to a study published online Dec. 8 in the Annals of Internal Medicine. Caitlin W. Hicks, M.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues examined the associations between PN and...

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