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No increased risk for thyroid cancer seen with use of GLP1 receptor agonist versus DPP4 inhibitor use, SGLT2 inhibitor use Glucagon-like peptide 1 (GLP1) receptor agonist use does not appear to be associated with an increased risk for thyroid cancer, according to a study published online April 10 in The BMJ. Björn Pasternak, M.D., Ph.D., from...

Increased risk for all-cause mortality seen with postpartum young-onset breast cancer in women with germline BRCA pathogenic variants Young-onset breast cancer (YOBC) with germline BRCA pathogenic variants (PVs) is associated with an increased risk for all-cause mortality if diagnosed within 10 years after childbirth, according to a study published online April 19 in JAMA Network Open. Zhenzhen Zhang,...

Achievement of ≥75 percent reduction in Psoriasis Area and Severity Index lower in both current, former smokers Tobacco smoking is negatively associated with resolution of psoriasis symptoms, according to a study published in the April issue of Tobacco Induced Diseases. Yan Qiang, from the School of Medicine at Tongji University in Shanghai, and colleagues explored the...

A retrospective analysis finds that patients who undergo pneumonectomy or are aged 70 years or older after receiving neoadjuvant concurrent chemoradiation therapy experience less favorable surgical outcomes. Lung cancer, particularly stage IIIA–N2 non-small cell lung cancer (NSCLC), is one of the leading causes of cancer-related deaths worldwide. The most effective treatment approach for this type...

Neoadjuvant chemoimmunotherapy, whether compared to immunotherapy alone or in combination with apatinib, may lead to increased surgical complexity while maintaining an acceptable incidence of postoperative complications, according to the results of a retrospective study. Lung cancer, specifically non-small cell lung cancer (NSCLC), is the leading cause of cancer-related deaths worldwide, accounting for nearly 85% of...

In a retrospective study, patients without a social support network had a shorter survival rate than those with support. Non-small cell lung cancer (NSCLC) continues to be a significant health issue and is a leading cause of death in many countries. Although there are promising new treatments available for certain types of lung cancer, managing...

A cohort study finds that class-switched B cells could potentially be used as a prognostic marker for non-small cell lung cancer and as a target for future therapeutic strategies. Lung cancer is a major global health concern. Significant progress has been made in treatment, with immunotherapy emerging as a recent breakthrough of great promise. The...

Nonhormonal pharmacotherapies that are effective in treating postmenopausal vasomotor symptoms include serotonin–norepinephrine reuptake inhibitors such as desvenlafaxine and venlafaxine. In a recent literature review, these pharmacological treatments were found to be safe, efficacious, and well-tolerated. Approximately 60–80% of menopausal women experience vasomotor symptoms during the initial 7 years of the onset of menopause, which have...

A retrospective study found that the total healthcare costs in menopausal women treated for vasomotor symptoms were moderately greater compared to those of untreated menopausal women  Vasomotor symptoms are the predominant symptoms among menopausal women; however, these mostly remain untreated. While hormone therapy is the commonly administered treatment option, the lack of compliance with this...