December 21, 2021
Racial Differences in Tumor Mutation Burden Testing
Tumor mutational burden (TMB) refers to the total number of non-inherited mutations found in the DNA of cancer cells and can help determine the best course of treatment. This retrospective study, published in Future Oncology, focuses on the use of tumor mutational burden testing in pan-tumor populations. So far, there is limited real-world information regarding...
Leveraging Epigenomic Variation Across Cancer Cell Lines
It is well understood that epigenetic dysregulation can contribute to the formation of tumors and that gene expression variations impact how well tumors respond to treatment and how tumors can progress. However, despite advancements in profiling techniques, it is unclear how epigenetic alterations contribute to cancer cellular properties, such as heterogeneity, stemness, and chemoresistance. To better...