March 23, 2022

Head and neck cancer is the sixth most prevalent cancer, with an annual incidence of more than 600,000 cases and a worldwide mortality rate of 350,000 deaths a year. Surgery, chemotherapy, and radiotherapy are the treatment modalities of choice. Induction chemotherapy (IC) is sometimes advised in select patients based on organ preservation considerations due to...

For advanced prostate cancer, androgen deprivation therapy (ADT) has been the cornerstone of systemic therapy. The most common treatment is testosterone suppression and bicalutamide, a nonsteroidal androgen receptor antagonist.  Enzalutamide is a second-generation androgen receptor inhibitor that inhibits nuclear translocation and DNA binding in prostate cancer cells, resulting in increased cytotoxicity. This study, published in JAMA...

Proposed changes to voluntary federal guidelines for prescribing opioid painkillers emphasize that doctors should first try other treatments for acute, subacute, and chronic pain. The non-opioid treatment options suggested by the U.S. Centers for Disease Control and Prevention include prescription medications like gabapentin and over-the-counter painkillers like ibuprofen (Advil, Motrin), as well as physical therapy, massage, and...