October 24, 2022

Black men exhibit higher rates of prostate cancer for many complex reasons. This article explores both the social and genetic factors at play. Among all forms of cancer, prostate cancer displays the widest racial disparities, which persist at every stage that the cancer presents. This article, published in Prostate Cancer and Prostatic Diseases, analyzes these...

Although about 18% of patients with multiple myeloma in the United States are Black, they represent only 4% of clinical trial participants. This article describes why this occurs, what the consequences are, and how this situation can be remedied This article, published in Blood Advances, describes the demographic representation in multiple myeloma (MM) clinical trials....

The way that multiple myeloma cells distribute throughout the body can relate to treatment types and disease progression in various ways. Imaging can be a robust source of useful information in these cases. This article, published in Nature Communications, attempts to address the evolution of multiple myeloma (MM) in whole bone marrow, in order to...

Breast cancer diagnosis by mammography is an important step in detection, but overdiagnosis can also be an issue. Researchers find that overdiagnosis is fairly common. Breast cancer mammography screenings can lead to screen-detected breast cancer that, if not detected, would not have caused any signs or symptoms during the patient’s lifetime. There is no consensus...

Obesity has a demonstrable relationship to increased rates of breast cancer. Although the mechanisms are not fully clear, certain pathways towards improved treatment are suggested. Obesity, which is especially common in the United States, can promote both the onset and progression of numerous types of cancer, including breast cancer. Both breast cancer and obesity are...

In a unanimous vote on Thursday, a panel of U.S. vaccine experts recommended that COVID-19 shots be added to the list of recommended vaccinations for children and adults. Now it is up to the U.S. Centers for Disease Control and Prevention to decide whether to follow the advice of its Advisory Committee on Immunization Practices....

Bipolar disorder (BD) is causally associated with inflammatory bowel disease (IBD), according to a study published online Sept. 20 in Frontiers in Genetics. Zhe Wang, from the First Affiliated Hospital, China Medical University in Shenyang, and colleagues performed bidirectional two-sample Mendelian randomization (MR) and selected single nucleotide polymorphisms (SNPs) associated with BD and IBD. SNPs...

Advances in gene therapies and drug development have led to a resurgence in research for more effective sickle cell anemia treatments. This article discusses stem cell transplant options and avenues of drug development. Sickle cell anemia (SCA) results from a point mutation in the gene for the beta globin chain of hemglobin. After delivering oxygen,...