December 19, 2022
Tecovirimat and Other Antivirals for Human Monkeypox Infection
Antivirals including tecovirimat, cidofovir, brincidofovir, trifluridine, and vaccinia immune globulin, have been utilized to treat human monkeypox virus infection (MPXV), according to the first systematic study of the topic. The most widely utilized of these is tecovirimat, which has proven beneficial with no significant safety risks. The World Health Organization recently designated the human monkeypox...
The Need for Vaccines for COVID-19 Variants
Several COVID-19 vaccines have been developed, but additional effective vaccines are still needed to meet the global demand. A study showed that the fast appearance and spread of SARS-CoV2 variants of concern (VOCs), which have the potential to evade neutralizing antibodies or cell-mediated immunity, can jeopardize vaccine effectiveness (VE). Several pneumonia cases with unclear etiologies...
Low-Certainty Evidence Behind Ivermectin for COVID-19
The antiparasitic drug ivermectin inhibits in-vitro replication of viruses. However, there has been conflicting information about the effectiveness of ivermectin for treating COVID-19 and preventing SARS-CoV-2 infection. COVID-19 infections require affordable, widely accessible, and efficient treatments. Ivermectin’s effectiveness in treating COVID-19 infections has yielded conflicting results in clinical trials. The drug is believed to work...