January 9, 2023

Patients with NMOSD who have non-immune-related comorbidities face unique challenges in their treatment. This study examined their demographics and risk factors. Among patients with neuromyelitis optica spectrum disorders (NMOSD), those with comorbidities may have unique clinical features, prognoses, and treatment outcomes. Comorbidities may affect various systems of the body, and this study, published in the...

This study provides a longitudinal analysis of NMOSD outcomes using modern treatment methods and finds more promising results than past studies have shown. Even in patients who undergo immunosuppressive or immunomodulatory therapy, neuromyelitis optica spectrum disorder (NMOSD) tends to follow a progressive disease course with step-wise accumulation of disability over time. The influence of aquaporin-4...

The role of dsDNA in the cerebrospinal fluid of patients with NMOSD is not fully understood, but researchers have found that the levels are higher in this population. Neuromyelitis optica spectrum disorder (NMOSD) causes inflammation in the central nervous system and results in severe myelitis and optic neuritis. Double-stranded DNA (dsDNA) has been found to...

Key Takeaways The EPA’s new proposed standards on fine particle pollution — soot — would be the first update since 2012. This tiny pollution stems from the burning of fossil fuels and is linked to asthma, heart and lung disease, and premature death. Those most affected by PM2.5 are children, older adults, heart and lung...

Cluster of inflammation markers positively associated with multiple sclerosis-related species Considerable alterations in the gut microbiota are seen in patients with multiple sclerosis, according to a study published online Jan. 5 in Genome Medicine. Florence Thirion, from Université Paris-Saclay, and colleagues conducted a case-control study involving 148 Danish cases with multiple sclerosis and 148 matched healthy...