February 15, 2023

Black children are overreported as suspected victims, at a rate of 2.5 times their proportion in the overall U.S. population Black children with traumatic injuries are overreported as suspected victims of child abuse, according to a study published in the February issue of the Journal of Pediatric Surgery. Modupeola Diyaolu, M.D., from the Stanford University School...

Increased odds of 30-day mortality ranges from 2.46 to 1.23 for nontraumatic coma and stroke. Neighborhood socioeconomic status (SES) is associated with 30-day mortality for common neurologic conditions, according to a study published online Feb. 15 in Neurology. Jay B. Lusk, from the Duke University School of Medicine in Durham, North Carolina, and colleagues examined the...

Key Takeaways Yet another study confirms what millions who have had COVID already know: Symptoms linked to the infection can linger for months. More than 7 in 10 patients reported coughing, heartbeat irregularities and breathlessness six months later, while half suffered from fatigue and physical limitations. Not only that, more than half also said they had...

Key Takeaways Advisers to the U.S. Food and Drug Administration will discuss over-the-counter purchase of a nasal spray that can reverse an opioid overdose The spray — generic naloxone hydrochloride — can already be obtained without a prescription, but currently buyers must get it from a pharmacist Experts say removing that requirement could remove some...

A retrospective study found that Black patients with vitiligo have high rates of comorbid autoimmune diseases. Vitiligo is a condition that causes loss of skin color in patches that can get larger over time. A 2020 retrospective study examined the diseases associated with vitiligo in the New York City population.  The researchers evaluated the data...

Vitiligo research has historically lacked diversity, but studies using a more representative sample are attempting to minimize the gap in understanding. Vitiligo patients of historically marginalized groups carry a greater burden of disease. Research has been conducted on homogenous populations of mostly White individuals. New analysis of a diverse cohort characterized different patterns of diagnosis...

Ruxolitinib, an easy-to-use topical medication for vitiligo has recently been approved by the FDA. The cream can be applied by patients at home, making it a practical option. Vitiligo is a complex autoimmune disorder affecting the skin. Destruction of melanocytes from autoreactive immune activity causes patches of white skin to develop anywhere on the body....

Vitiligo, an autoimmune disorder resulting in skin depigmentation, can be treated with mesenchymal stem cells that target immune pathways involved with inflammation and skin cell regeneration. Mesenchymal stem cells are being proposed for the treatment of vitiligo. In vitiligo, reactive oxygen species and immune responses cause damage to skin cells. Stem cell therapy can regenerate...

siRNAs are used to treat diseases by silencing genes, and in the case of autoimmune skin diseases like vitiligo, blocking the production of the IFN-γ receptor gene may prevent disease-causing immune responses in the skin.  Small interfering RNAs (siRNAs) are being used to treat diseases by silencing gene expression. In autoimmune skin diseases such as...