February 20, 2023

Vitiligo increases the risk for thyroid disease, especially in women. These autoimmune disorders should be integrated into the decision-making process around screening for diseases. Autoimmune thyroid disease is more common in people with vitiligo. Women are more likely to have both vitiligo and a thyroid disorder. Vitiligo should be considered a risk factor for other...

In vitiligo, regulatory T cells suppress autoimmune responses that worsen disease, but only if they contain the chemokine receptor CCR6, according to a recent study. Effector T cells destroy melanocytes, leading to vitiligo lesions. Regulatory T cells suppress effector T cell activity and improve disease. The chemokine CCR6 is necessary to bring regulatory T cells...

Treatments for vitiligo are most effective when started early, with those experiencing later onset and less affected skin surface area receiving treatment sooner. Several demographic and disease-related factors are associated with treatment delays in vitiligo patients.  Treatments for vitiligo are most effective when delivered early in the disease course. People with vitiligo onset after age...

Vitiligo lesions can be treated with antibodies, but off-target effects may be harmful. Injection with a bispecific antibody returns pigmentation only to the area of injection and limits systemic side effects. Vitiligo, an autoimmune condition, can be treated with immunosuppressant drugs. Local injection of skin lesions is preferable to systemic treatment because off-target side effects...

Stable vitiligo skin lesions have a distinct cellular makeup compared to active vitiligo melanocytes due to their unique genetic signatures and metabolic profiles, causing proinflammatory responses and a “stressed” cellular state. Stable vitiligo lesions have cellular profiles that are distinct from those of active vitiligo melanocytes. Keratinocytes in depigmented lesions have distinct genetic signatures and...

Based on a 2019 study, non-Hispanic Black and Hispanic children have higher rates of school absences due to AD. Atopic Dermatitis (AD), also known as eczema, is more severe in minority children, with Black children having a higher incidence rate than White or Hispanic children. Based on this 2019 study published in JAMA Dermatology, non-Hispanic...

According to this study, minorities are less likely to seek healthcare intervention for eczema despite having more severe cases. Eczema, also known as atopic dermatitis (AD), is a common chronic inflammatory disease of the skin. Based on information from this cohort study published in the Journal of American Academic Dermatology, in the United States, eczema...

This study provides a thorough meta-analysis of the relationship between vision problems and ADHD, with findings that could impact ADHD diagnosis methods. To date, there has been no systematic review and meta-analysis regarding the possible relationship between attention-deficit/hyperactivity disorder (ADHD) and disorders of the eye or altered visual function. This study, published in Molecular Psychiatry,...

Mepolizumab and benralizumab significantly improve lung function and minimize or prevent exacerbations and oral corticosteroid use. Asthma is a chronic, heterogeneous inflammatory disease of the lungs caused by different cells and inflammatory mediators and largely defined by genetics, that causes bronchial hyperreactivity and airflow limitation, resulting in recurrent wheezing, dyspnea, and exacerbations. It is a...