March 13, 2023

Targeting Metabolic Pathways for Asthma Treatment in Patients With Obesity

Treatments for metabolic disorders, like diabetes and obesity, can benefit patients with asthma who are at an increased risk of severe asthma due to obesity. Traditional asthma treatments may be less effective in obese patients. Obesity increases the risk and severity of asthma. Hypoglycemic therapies for type 2 diabetes and obesity may be beneficial for...

Plastic Chemical Exposure in Pregnancy: Long-Term Effects on Children’s Asthma

Recent studies reveal that prenatal exposure toBPAs and phthalates, harmful chemicals commonly found in plastics, can increase the risk for respiratory conditions, including asthma, and have long-term effects on the immune system. Harmful chemicals found in plastics can have long-term effects on the immune system. BPAs and phthalates can cross the placental barrier, posing long-term...

Diverse Genome-Wide Association Study Finds New Genetic Loci for Asthma

In a groundbreaking meta-analysis of over 150,000 individuals with asthma, 49 new genetic loci were identified. Asthma affects millions of people worldwide, but its genetic underpinnings are not well understood. The prevalence of asthma is variable in different parts of the world and in different populations within countries, but the heterogeneity cannot be explained solely...

COVID-19 Vaccination Safety for People With Multiple Sclerosis

The effects of COVID-19 vaccination on people with multiple sclerosis has not been studied in sufficient detail. This study provides an analysis of the available data. COVID-19 infection as well as the various COVID-19 vaccines have caused health complications for some patients with certain medical conditions. Despite the vaccine being available for a number of...

Disease Activity and Gut Microbiota in Patients With MS

The gut microbiome of patients with multiple sclerosis appears to be altered in characteristic ways that may inform future therapeutic approaches. Although multiple sclerosis (MS) is a chronic disease that affects the brain and spinal cord, it has been hypothesized that a disrupted bacterial and viral gut microbiota contributes to the pathogenesis of the disease....

Using AI-Generated Images for Identifying Cortical Lesions in MS Patients

Researchers were able to use AI-generated images as accurately as MRI-acquired images to identify lesions.  Although cortical multiple sclerosis (MS) lesions are clinically significant, they are often hard to evaluate using conventional clinical MRI. Double inversion recovery (DIR) and phase-sensitive inversion recovery (PSIR) are more sensitive but tend to be unavailable in many clinical settings. In...

Effects of the COVID-19 Pandemic on People With MS

People with MS deal with various types of burdensome effects of their disease. This study analyzed these effects in the context of the COVID-19 pandemic. The COVID-19 pandemic had wide-ranging impacts on mental health symptoms and quality of life. This change was apparent in both the general population and those with varying mental and physical...

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