March 16, 2023

Higher rates of vaccination seen in older patients; lower rates seen for metastatic solid tumors, with comorbidities For patients with cancer, age, cancer type, and comorbidity are associated with differential COVID-19 vaccine uptake rates, according to a study published online March 15 in Cancer. Dax Kurbegov, M.D., from the Sarah Cannon Research Institute in Nashville, Tennessee,...

Approval of Daybue applies to adults and children aged 2 years and older The U.S. Food and Drug Administration has approved Daybue (trofinetide) for the treatment of Rett syndrome in adult and pediatric patients aged 2 years and older. Approval was based on results from the phase 3 LAVENDER study in which the efficacy and...

Almost everyone has trouble sleeping occasionally, but when you toss and turn often enough that it affects your health, moods and safety, your bad nights of sleeping may be elevated to the level of a sleep disorder. Sleep disorders are among the most common medical problems that health care providers see in their practices, according...

Here’s a sobering stat: heart disease is the No. 1 cause of death for men and women, according to the Centers for Disease Control and Prevention (CDC). The good news? You can take actionable steps to improve your heart health and lower your chances of developing heart disease. What is heart disease? Heart disease is an...

The pathogenesis of MS is complex and may relate to various viral conditions. This study analyzes the way that various viruses affect MS onset, and what that can teach us about future therapies. Compared to other self-limiting myelin disorders, multiple sclerosis (MS) is associated with chronic inflammation in the central nervous system. Although its cause...

This study found a positive correlation between risk for colorectal cancer and early life body size owing to the retention of large body size into adulthood. Childhood obesity has an increasing prevalence across most geographic regions and serves as a major public health challenge globally. A Mendelian randomization study suggested a positive correlation between the...

Researchers assessed the accuracy of algorithm identification of individuals with type 1 diabetes who self-reported their race. Identification of individuals with type 1 diabetes for biomedical research is increasingly being done with the use of automated algorithms and electronic health records. However, the accuracy of the algorithms is unknown when accounting for self-reported race. A...

The onset of cardiometabolic conditions, like diabetes, occurs in younger ages for Black and Hispanic women as compared to White women. A 2022 cohort study published in JAMA Network Open evaluated racial/ethnic disparities in age-of-onset for four cardiometabolic outcomes. The study also accounted for multiple forms of potential selection bias. The cardiometabolic outcomes examined were...