August 2, 2023

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 A real-world data-derived algorithm was determined to be a feasible and accurate method for assessing treatment response in patients with multiple myeloma. Findings suggest that the derived response algorithm can consistently reproduce response assessments in patients with multiple myeloma in a clinical trial...

Isatuximab plus bortezomib, lenalidomide, and dexamethasone is feasible and effective for newly diagnosed multiple myeloma patients who are ineligible or have no intent for autologous stem cell transplantation. Newly diagnosed multiple myeloma (NDMM) patients ineligible for autologous stem cell transplantation (ASCT) have lower survival rates. Bortezomib (trade name Velcade)+lenalidomide (trade name Revlimid)+dexamethasone (VRd) is a...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 The combination of isatuximab, carfilzomib, and dexamethasone was found to be safe and efficacious for the treatment of relapsed multiple myeloma. Triplet regimens consisting of a proteasome inhibitor or immunomodulatory drug, a monoclonal antibody, and dexamethasone have substantially improved clinical outcomes in relapsed...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 Regular exercise for 6 months reduces the regular inhaled corticosteroid dose without limiting asthma. Inhaled corticosteroids (ICS) are the primary form of asthma treatment currently in use. These powerful anti-inflammatory drugs improve asthma control, maintain lung function, and prevent exacerbations by reducing airway...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 Compared to a written action plan alone, a digital action plan was used less frequently and did not affect the number of unscheduled medical contacts in this study. One strategy for managing asthma symptoms is a patient-tailored asthma action plan, including self-management instructions....

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 Atopic dermatitis increases the risk of asthma and other allergy-related symptoms. Other atopic and allergy conditions are also common. This includes asthma (10–30% of cases), food allergies, allergic rhinitis, allergic conjunctivitis, and eosinophilic disorders. This narrative review, published in the Asian Pacific Journal...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 An open-label placebo alleviated seasonal allergy symptoms, whereas a conventional placebo had no effect. Allergic rhinitis symptoms fluctuate with seasonal allergen levels. There is evidence that placebos are effective as symptomatic treatments. New research challenges the idea that placebo effects need deception by...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 For treating patients with chronic pruritus, narrowband ultraviolet B was found to be equivalent to broadband ultraviolet B. In inflammatory skin conditions, phototherapy is an important treatment technique. Ultraviolet light therapy may reduce pruritus in people who suffer from chronic pruritus (CP), whether...

Medically reviewed by Dr. Samuel Sarmiento, M.D., MPH on August 3, 2023 Maternal egg intake during the early neonatal period did not influence the development of immunoglobulin E-mediated egg allergy or sensitization to eggs in a recent study. Around 10% of children are believed to suffer from food allergies, which are rising rapidly. It has...