August 10, 2023

To date, research efforts on excess postpartum weight retention have been largely focused at the individual level. Investigations are needed to determine the factors contributing to ethnic and racial disparities in postpartum weight retention.  Approximately 75% of people who give birth tend to exhibit postpartum weight retention, which is further associated with the risk of...

The integration of the culturally adapted intervention and behavior change procedures in this study did not contribute to significant changes in the dietary intake of the given population.  An unhealthy diet is associated with several health risks, including childhood obesity. This study investigated the effect of an innovative obesity prevention intervention on the quality of...

In this study, several health problems in nursing home patients were significantly associated with obesity. These results indicate that healthcare teams in nursing homes should monitor the nutritional status of patients and ensure a healthy weight while preserving muscle mass so as to prevent any weight-related health complications.  Previous studies have indicated an increase in...

Implementing a voluntary food reformulation policy led to substantial changes in the consumption of excessive sugar, which was associated with overcoming commercial, operational, and technical barriers.  The Childhood Obesity Plan in the UK targets the reduction of sugar and energy in dietary components via a voluntary sugar-reduction program. This study aimed to assess the success...

A hypocaloric balanced diet intervention was associated with enhanced weight loss, which could be explained by diet-induced modifications in the gut microbiota. Gut microbiota varies from person to person and has variable effects on host metabolism. In obese individuals, characteristic responses to various dietary patterns have been observed. Hence, it can be inferred that gut...

Medically reviewed by Dr. Shani S. Saks, D.O. on August 2, 2023 In a phase 3 trial, ciltacabtagene autoleucel caused a significantly lower risk of disease progression or death than standard care in lenalidomide-refractory multiple myeloma patients. The frequency of lenalidomide resistance early in multiple myeloma (MM) treatment is increasing, leading to a need for...

Medically reviewed by Dr. Shani S. Saks, D.O. on August 2, 2023 Patients in a phase 1–2 study who were treated with teclistamab demonstrated a high rate of durable and deep therapeutic response. The treatment was safe and effective. Most of the toxic effects that were associated with T-cell redirection were categorized as grade 1...

Medically reviewed by Dr. Shani S. Saks, D.O. on August 2, 2023 In a phase 1 study, talquetamab induced a substantial therapeutic response in patients suffering from multiple myeloma. The bispecific antibody was safe except for low-grade cytokine release syndrome, dysgeusia, and skin-related events. Malignant plasma cells in multiple myeloma express the G protein-coupled receptor,...

Medically reviewed by Dr. Shani S. Saks, D.O. on August 2, 2023 Ide-cel therapy significantly improved response and progression-free survival compared to standard regimens in triple-class-exposed relapsed and refractory multiple myeloma patients. Relapsed and refractory multiple myeloma (MM) patients with triple-class exposure display suboptimal responses to standard therapies, leading to poor survival outcomes. Idecabtagene vicleucel...