September 23, 2023

Gender disparities exist in various aspects of ATTR-CA, a condition predominantly affecting males. Transthyretin cardiac amyloidosis (ATTR-CA) is a progressive disease characterized by abnormal transthyretin deposition in cardiac tissue. Recent research suggests that sex differences may play a significant role in the disease’s clinical manifestations, progression, and outcomes.  A study in the journal Heart Failure...

Transthyretin cardiac amyloidosis prevalence in the transcatheter aortic valve replacement population is lower than previously described, and NT-pro BNP can guide screening, according to a recent study. Transthyretin cardiac amyloidosis (ATTR-CA) prevalence in aortic stenosis patients is 5–20%, with higher rates in those who underwent transcatheter aortic valve replacement (TAVR) vs. surgical aortic valve replacement...

Tafamidis slowed cardiac remodeling and potentially lowers amyloid deposition in patients with hereditary A97S transthyretin cardiomyopathy in a recent study. Transthyretin amyloid cardiomyopathy (ATTR-CM) is a rare but life-threatening disease. Tafamidis decreases amyloid formation and is an effective treatment for ATTR-CM. There are differences in the level of cardiac involvement among disease variants. Up to...

Over-the-counter 1% colloidal oatmeal cream effectively treats mild-to-moderate atopic dermatitis in Black children, according to a recent study. Atopic dermatitis (AD) is one of the most common skin conditions among children in the United States. Its prevalence varies with race and ethnicity, with Black children being 1.7 times more likely to develop AD than White...

Patient race and specific atopic dermatitis diagnoses are associated with differences in dupilumab prescription patterns. Atopic dermatitis (AD) is a common chronic inflammatory disease. Treatment with a systemic immunomodulating agent is indicated in moderate-to-severe AD. These systemic agents include cyclosporine, azathioprine, methotrexate, mycophenolate mofetil, and systemic steroids. Dupilumab, a fully human monoclonal antibody, may be...

Atopic dermatitis severity and treatment patterns do not differ among diverse racial and ethnic groups in the United States, according to a recent study. Atopic dermatitis (AD) has heterogeneous manifestations across regional and racial groups. Previous studies in the United States found racial and ethnic differences in AD disease patterns, including risk factors for severity,...

Air pollutants such as nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2), and ozone (O3) are linked to the prevalence and severity of atopic dermatitis. These contaminants have been linked to an increased risk of AD during pregnancy, childhood, and maturity. Atopic dermatitis (AD) is a chronic, inflammatory skin disease affecting approximately 20% of...