September 27, 2023

Greater improvement seen in disease severity by 12 weeks with ciclosporin, but MTX was superior by 60 weeks For children and young people with severe atopic dermatitis (AD), ciclosporin (CyA) and methotrexate (MTX) are both effective over 36 weeks, according to a study published online Sept. 19 in the British Journal of Dermatology. Carsten Flohr, Ph.D.,...

Icodec with app superior to once-daily basal insulin analogues for change in glycated hemoglobin For insulin-naive adults with type 2 diabetes, once-weekly insulin icodec (icodec) titrated with a dosing guide app (icodec with app) is superior for change in glycated hemoglobin A1c (HbA1c) level versus once-daily basal insulin analogues (OD analogues), according to a study...

Of 149 patients with baseline disability, 54 percent improved, 37 percent were stable, 9 percent deteriorated Autologous hematopoietic stem cell transplantation (aHSCT) for treatment of relapsing-remitting multiple sclerosis (RRMS) yields freedom from disease activity for most patients, according to a study published online Sept. 25 in the Journal of Neurology, Neurosurgery & Psychiatry. Thomas Silfverberg, M.D.,...

Increased risk for suicide seen among registered nurses, health technicians, health care support workers versus non-health care workers Registered nurses, health technicians, and health care support workers have an increased risk for suicide compared with non-health care workers, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association....

Discrimination based on race in the criminal justice system may contribute to Black adult COVID-19 vaccine hesitancy.   COVID-19 was the third-most significant cause of mortality across the United States in 2020. In 2019, the World Health Organization declared vaccine hesitancy a top-ten global health problem. Hesitancy concerning the COVID-19 vaccine is decreasing along racial...

A community-based lifestyle intervention program called Black Impact was studied for the purpose of determining its impacts on the social needs of Black men and its potential to mitigate the effect of social needs as contributors to worse health outcomes. The study found that the program reduced the social needs of Black men, but no...

Cetuximab maintenance therapy for wild-type metastatic colorectal cancer is associated with clinically significant overall and progression-free survival. However, cetuximab therapy following FOLFIRI plus cetuximab is not appropriate for patients with mutated mitogen-activated protein kinase, warranting refined treatment strategies. There continues to be a lack of consensus regarding the best option among de-escalation modalities for managing...

A recent study found that elimination of race and ethnicity as risk predictors for colorectal recurrence is associated with worsened fairness of the risk prediction model, resulting in inappropriate care for ethnic and racial minorities in the population. The inclusion of racial and ethnic parameters in the risk prediction models is often inadequate, reflecting the...

The results of an MRI-based study show that patients with squamous cell cervical cancer with unclear tumor borders have a worse prognosis, lymph node metastases, and distant recurrence. One of the most common forms of cancer among women is cervical cancer. About 10,000 Japanese women are diagnosed with cervical cancer annually, and approximately 3,000 will...