October 6, 2023

Maintenance darunavir/ritonavir monotherapy was effective in the prevention of perinatal HIV transmission in a recent study; however, about 10% of the cases required treatment intensification. Nucleoside reverse transcriptase inhibitors (NRTIs) are associated with drug-related toxicities in both fetal and neonatal stages. However, despite known toxicities, NRTIs are recommended for neonatal prophylaxis against HIV during pregnancy. ...

Opioid agonist therapy and needle and syringe programs are effective in reducing the transmission of HIV, HCV, and injecting risk behavior, according to a recent review. The prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) is associated with injecting risk behavior in people who inject drugs (PWID). This systematic review updated an...

Microarray patches were found to be acceptable as both multipurpose prevention technology and pre-exposure prophylaxis among participants of a recent study; however, some participants expressed a preference for multipurpose prevention technology. Microarray patches (MAPs) are being developed as a multipurpose prevention technology (MPT) in order to prevent unplanned pregnancies and human immunodeficiency virus (HIV) infection....

Sulfated endospermic nanocellulose crystals were shown to have antiviral activity by irreversibly interacting with viral particles via cross-linking, thereby inhibiting viral infections. Sulfated endospermic nanocellulose (ENC) crystals are biomaterials that have antimicrobial activity. ENC can be derived from the parenchyma of ivory nut endosperm and used against microbes after its binding capacity is enhanced by...

A literature review found that long-acting injectable cabotegravir is effective for the prevention of HIV; however, it may increase the risk of resistance to integrase strand transfer inhibitors in individuals with infection at the initiation or during the treatment process. Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) pose a significant health burden,...

Staff Writer: Andre McGowan Cell-free DNA is reported to be an authentic diagnostic biomarker in breast cancer patients. A recent study supports this, noting significantly increased levels of cell-free DNA in a group of breast cancer patients. Increased levels of cell-free deoxyribose nucleic acid (cfDNA) in cancer cells are associated with a reduction in the...

With the development of more potent treatment options, the survival rate for Hodgkin lymphoma has increased over time. Treatment options for children with Hodgkin lymphoma (HL) have changed dramatically over the years, mainly as a result of developments in radiation therapy (RT) and chemotherapy (ChT). In the past, both children and adults received the same...