December 12, 2023

Interleukin-33 can lead to blood–brain barrier dysfunction, mediating the intrathecal production of immunoglobulins in myelin oligodendrocyte glycoprotein antibody disease and aquaporin-4 neuromyelitis optica spectrum disorder. Interleukin-33 is correlated with central nervous system demyelinating diseases.
Neurology
Neuromyelitis Optica Spectrum Disorder

Interleukin-33 Biomarker Affected Intrathecal Immunoglobulin Synthesis in NMOSD and MOGAD

Interleukin-33 can lead to blood–brain barrier dysfunction, mediating the intrathecal production of immunoglobulins in myelin oligodendrocyte glycoprotein antibody disease and aquaporin-4 neuromyelitis optica spectrum disorder. Interleukin-33 is correlated with central nervous system demyelinating diseases. The autoimmune conditions of the central nervous system (CNS) include myelin oligodendrocyte glycoprotein antibody disease (MOGAD) and neuromyelitis optica spectrum disorder...

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