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Aquaporin-4-Mediated Th17 Cytokine Response in Neuromyelitis Optic Spectrum Disorder

A new ex vivo study shows that the AQP4-IgG/AQP4 immunocomplex-mediated cytokine response plays a vital role in neuromyelitis optica spectrum disorder pathogenesis. Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease particularly affecting the optic nerves and spinal cord. Unlike multiple sclerosis (MS), NMOSD exhibits unique clinical features and diagnostic criteria, with aquaporin-4 immunoglobulin...

Cancer

HIV/AIDS

HIV and Cancer: Insights From an IARC- and NCI-Sponsored Workshop

A comprehensive workshop hosted by the International Agency for Research on Cancer and the National Cancer Institute highlights evolving patterns and research priorities in the relationship between HIV and cancer, offering new directions for managing these complex health challenges. Approximately 38 million people globally are living with HIV. This population is at increased risk for...

Cardiovascular Risk Management

Health Disparities

HIV/AIDS

Mental Health

Social Determinants of Health Impact HIV and Heart Failure Outcomes

A recent review reveals significant impacts of social determinants like socioeconomic status, education, and geography on health outcomes for individuals with HIV and heart failure, emphasizing the need for holistic healthcare strategies. This insight may help in addressing complex health challenges and advancing integrated care approaches. A narrative review published in the journal Cureus delves...