Contributions
Neuromyelitis Optica Spectrum Disorder Prognosis Affected by Age of Onset
Patients with NMOSD who develop the condition at a later age are at a higher risk of experiencing severe symptoms. An inflammatory condition of the central nervous system known as neuromyelitis optica spectrum disorder (NMOSD) is characterized by recurrent episodes of optic neuritis (ON) and longitudinally widespread transverse myelitis. Patients with NMOSD who have an...
Pain and Plasma C5a in Neuromyelitis Optica Spectrum Disorders
Neuromyelitis optica spectrum disorder patients have elevated plasma C5a and inflammatory cytokine levels during remission periods. Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease that affects the central nervous system (CNS), resulting in inflammation of specific brain regions, optic nerve, and spinal cord. NMSOD patients have increased complement component C5a and associated inflammatory...
Neuropathic Pain Factors in Neuromyelitis Optica Spectrum Disorder Patients
Depression and initial spinal cord involvement are among the factors associated with neuropathic pain in patients diagnosed with neuromyelitis optical spectrum disorders. Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disorder with severe demyelination, especially of the optic nerve, brain, and spinal cord. Neuropathic pain is a common yet underrecognized symptom of NMOSD. The...
Feds Will Start Limiting Telehealth Prescriptions for Painkillers, ADHD Drugs
Patients will be required to see a doctor in person to get a first prescription for opioids, ADHD drugs Federal officials plan to tighten access to drugs that have the potential for abuse by reinstating federal prescribing requirements that were loosened during the pandemic. The Biden administration will require that patients see a doctor in...
FDA Approves First Home Test to Detect Both Flu and COVID-19
Test will be sold without a prescription and can be used by anyone 14 years and older or by an adult or children ages 2 years and older A new at-home test will help people struggling with upper respiratory symptoms figure out whether they have COVID-19 or the flu. The U.S. Food and Drug Administration...
1999 to 2021 Saw 50-Fold Increase in Methamphetamine Mortality
Proportion of deaths co-involving methamphetamine and heroin or fentanyl peaked at 61.2 percent in 2021 Methamphetamine-related mortality increased 50-fold from 1999 to 2021, and the proportion of deaths co-involving heroin or fentanyl also increased, according to a study published online Feb. 2 in the American Journal of Public Health. Rachel A. Hoopsick, Ph.D., M.P.H., from the...
CDC Warns of Rise of Drug-Resistant Shigella Bacteria
Shigella is easily spread, and limited treatment options exist for patients infected with XDR strains Public health officials are warning about an increase in drug-resistant strains of the bacteria Shigella. About 5 percent of Shigella infections reported to the U.S. Centers for Disease Control and Prevention last year were caused by the drug-resistant XDR strain. That compares to 0...
Inebilizumab for Treating Neuromyelitis Optical Spectrum Disorder
Inebilizumab therapy was determined to be effective for patients with prior exposure to rituximab; however, the majority of these patients experienced infections, increasing the need for vigilance. Neuromyelitis optica spectrum disorder (NMOSD) is a chronic and rare autoimmune inflammatory disorder affecting the central nervous system (CNS). NMOSD is characterized by repeated attacks of transverse myelitis,...
Relationship Between Life Quality and Disability Progression in NMOSD Patients
The quality of life of NMOSD patients corresponds to their degree of disability and can be improved with early interventions for preventing relapse. Neuromyelitis optical spectrum disorder (NMOSD) is a rare autoimmune disorder involving the spinal cord and optic nerves. There is a consistent and strong association between the quality of life (QoL) and disability...