Pediatrics

A phase III trial found that long-term dupilumab treatment demonstrated acceptable safety and sustained efficacy in children aged 6–11 years with severe atopic dermatitis. Atopic dermatitis (AD) is the most prevalent inflammatory skin disease in children. Treatment options are limited in children aged 6–11 years with severe AD inadequately controlled by topical therapies. Dupilumab has...

Greater improvement seen in disease severity by 12 weeks with ciclosporin, but MTX was superior by 60 weeks For children and young people with severe atopic dermatitis (AD), ciclosporin (CyA) and methotrexate (MTX) are both effective over 36 weeks, according to a study published online Sept. 19 in the British Journal of Dermatology. Carsten Flohr, Ph.D.,...

Over-the-counter 1% colloidal oatmeal cream effectively treats mild-to-moderate atopic dermatitis in Black children, according to a recent study. Atopic dermatitis (AD) is one of the most common skin conditions among children in the United States. Its prevalence varies with race and ethnicity, with Black children being 1.7 times more likely to develop AD than White...

This study found that Black and Hispanic children who live in poor neighborhoods, have public insurance, and have higher rates of comorbidities like allergies were also significantly more likely to be hospitalized for COVID-19. Although COVID-19 tends to be less severe in children, hospitalization rates among children increased fivefold in the summer of 2021, possibly...

An Americas Health Foundation panel agreed on the significant prevalence of health disparities related to atopic dermatitis in Latin America. They identified the factors contributing to these disparities and developed expert recommendations. Atopic Dermatitis (AD) is a chronic, heterogeneous skin disease. The condition has multiple risk factors, including genetics, environmental factors, immunological factors, and more....

A cross-sectional study found that disadvantaged and disordered neighborhood environments were associated with excess adiposity in adolescence. Adolescents living in disadvantaged neighborhoods are exposed to chronic stressors such as crime, violence, overcrowding, and food insecurity, which undermine their psychological and physical health. Stress exposure promotes unhealthy eating behaviors. Moreover, chronic stress can lead to the...

A low glycemic index/load diet showed no association with changes in cardiometabolic, glucometabolic, and anthropometric parameters in overweight and obese children in a recent study. Extensive research has focused on combinations of dietary interventions for preventing and treating childhood obesity. However, the effect of a low glycemic index (LGI) and low glycemic load (LGL) diet...

Test able to quantify diagnostic status as well as individual levels of social disability, verbal ability, and nonverbal ability. Objective measurements of social visual engagement through eye tracking-based measures can be used to aid in autism diagnosis and assessment, according to a study published online Sept. 5 in JAMA Network Open. Warren Jones, Ph.D., from Children’s...

This study found a negative association between asthma in children and the intake of docosahexaenoic acid in the diet, particularly in male children between 5 and 12 years of age with a history of maternal smoking during the gestation period.  The development of childhood asthma involves behavioral, genetic, and environmental changes. Polyunsaturated fatty acids (PUFA)...