OBGYN & Women’s Health

A systematic review explores the promising connection between ferroptosis, a form of regulated cell death, and triple-negative breast cancer, offering new insights into prognosis and treatment strategies. By identifying potential biomarkers and therapeutic targets related to ferroptosis, this research opens avenues for personalized treatment approaches to this form of breast cancer known for its aggressive...

A retrospective study used machine learning to predict treatment response and survival rates in breast cancer patients from an underserved, inner-city population. The study examined the impact of tumor subtypes and socioeconomic factors on outcomes. Machine learning models reveal no association between pathological complete response and patient demographics but highlight the significance of tumor subtypes...

New research shines a light on fighting a difficult type of breast cancer, known as triple-negative breast cancer, by focusing on an enzyme that protects these cancer cells. This discovery opens up possibilities for treatments that are not only effective but that may also be gentler on the body. Research identifies the enzyme NUDT5 as...

A preliminary study reveals that tiny particles released by cancer cells may predict the effectiveness of breast cancer treatment, particularly for those facing triple-negative breast cancer. This research offers a promising approach to personalizing treatment plans, potentially improving outcomes for patients and providing new hope to individuals and their families navigating this challenging diagnosis. Dealing...

A type of signalling molecule called filamin A may play a key role in the battle against triple-negative breast cancer. This research could lead to more personalized and effective treatments by targeting the unique ways filamin A influences cancer growth and spread, offering new hope for those affected by this type of cancer, which is...

Findings greater for Black pregnant women, but exist for White women facing greater social inequity Pregnant women facing less socioeconomic opportunity experience lower use of epidurals, particularly Black women, according to a study published online Feb. 1 in Obstetrics & Gynecology. Jean Guglielminotti, M.D., Ph.D., from Columbia University Vagelos College of Physicians and Surgeons in New...

First-trimester dyslipidemia in pregnant women with subclinical hypothyroidism is associated with an increased risk of adverse pregnancy outcomes, according to a recent cohort study. Subclinical hypothyroidism is associated with dyslipidemia and may have adverse pregnancy outcomes. This thyroid disorder is common during pregnancy, increasing the risk for small for gestational age infants, preterm birth, and...

Omalizumab in the treatment of chronic spontaneous urticaria was not associated with any negative maternal or fetal outcomes when administered before and after pregnancy, in a recent retrospective study. Omalizumab is a monoclonal antibody against immunoglobulin E (IgE) that is recommended for individuals with medication-resistant moderate-to-severe persistent asthma, chronic spontaneous urticaria (CSU), and nasal polyps...

Disparities no longer seen once a neuraxial catheter is in situ among those undergoing intrapartum cesarean delivery Racial disparities in the rates of general anesthesia use persist among patients undergoing cesarean delivery, according to a study published online Jan. 9 in JAMA Network Open. Caroline Leigh Thomas, M.D., from the University of Chicago Medical Center, and...