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Majority of U.S. Adults Give Health Care System a 'D' for Handling Mental Health

Cost, finding a provider, and stigma are top barriers to receiving treatment Three-quarters of U.S. adults believe mental health issues are identified and treated worse than physical health issues, according to the results of a survey released by West Health and Gallup. The web survey was conducted Feb. 2 to 14 and included 2,266 U.S....

321,566 Children Lost a Parent to Drug Overdose in 2011 to 2021

Highest rates seen among children of non-Hispanic American Indian or Alaska Native individuals From 2011 to 2021, an estimated 321,566 children lost a parent to drug overdose in the United States, according to a study published online May 8 in JAMA Psychiatry. Christopher M. Jones, Pharm.D., Dr.P.H., M.P.H., from the Substance Abuse and Mental Health Services...

Distal Symmetric Polyneuropathy Often Undiagnosed

Older age and metabolic syndrome were associated with DSP, while odds were lower for non-Hispanic Blacks Distal symmetric polyneuropathy (DSP) is common and is frequently undiagnosed, according to a study published online May 8 in Neurology. Melissa A. Elafros, M.D., Ph.D., from the University of Michigan in Ann Arbor, and colleagues examined whether data accurately reflect...

Persistent Sociodemographic Differences Seen in Use of AutoHCT for Multiple Myeloma

Patients with public/no versus private insurance were less likely to receive autologous HCT Sociodemographic differences persist in utilization of autologous hematopoietic cell transplantation (autoHCT) for multiple myeloma, according to a study published in the April issue of Clinical Lymphoma, Myeloma & Leukemia. Naseem S. Esteghamat, M.,D., from the University of California Davis Comprehensive Cancer Center in...

Surgical Techniques Improve Outcomes in Breast Cancer-Related Lymphedema

Recent advancements in surgical techniques for breast cancer-related lymphedema offer promising results. A study comparing vascularized lymph node transfer and lymphaticovenous anastomosis finds significant improvements in lymphatic drainage, particularly beneficial in severe cases of breast cancer-related lymphedema.  Vascularized lymph node transfer (VLNT) and lymphaticovenous anastomosis (LVA) are microsurgical techniques that enhance lymphatic drainage in patients...

Severe Hyponatremia With Immune Checkpoint Inhibitor Therapy in Mulvihill–Smith Syndrome

This case study reports the first known case of immune checkpoint inhibitor-induced hyponatremia due to syndrome of inappropriate antidiuretic hormone release in a patient with Mulvihill–Smith syndrome. Vigilant monitoring for hyponatremia is recommended for patients on immune checkpoint inhibitor therapy who are predisposed to malignancies. Key Points Immune checkpoint inhibitors (ICIs), administered for treating solid...

Dopamine-Secreting Carotid Body Paraganglioma in Patient With Succinate Dehydrogenase Subunit-B Mutation

A newly published case report illustrates the diagnostic and monitoring benefits of dopamine testing for patients who are suspected or at risk of having dopamine-secreting head and neck paragangliomas. Key Points Paragangliomas are rare neuroendocrine tumors that originate from neural crest cells. Hypersecretory paragangliomas, such as those that secrete dopamine, are rare and may go...

Pulmonary Metastatic Follicular Thyroid Carcinoma Without Intrathyroidal Primary Thyroid Cancer

The existence of pulmonary metastatic follicular thyroid carcinoma with the presence of a primary thyroid neoplasm is a rare phenomenon that should be differentiated from ectopic thyroid tissues and should be considered in the differential diagnosis. The presence of benign and malignant pulmonary thyroid tissue is a rare finding. Individuals with ectopic thyroid tissue can...

Ubiquitination Genes Linked to Liver Cancer Prognosis

A recent study identifies ubiquitination-related genes as crucial predictors of hepatocellular carcinoma outcomes, emphasizing their role in refining treatment strategies. The findings underline the importance of incorporating genetic insights into personalized therapeutic approaches for liver cancer patients. Hepatocellular carcinoma (HCC), a leading cause of cancer mortality globally, continues to challenge medical professionals. A study published...

MicroRNAs and Proteasome Inhibitors in Breast Cancer Treatment

Proteasome inhibitors show distinct effects on microRNA regulation in breast cancer cell lines, a new study reveals. These findings emphasize the potential for microRNA-targeted approaches to refine treatment efficacy in breast cancer therapies. Breast cancer remains a substantial cause of cancer-related mortality among women worldwide. This cell culture study, published in Clinical and Translational Oncology,...
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