April 8, 2022
Total Mesometrial Resection for Cervical Cancer
Total mesometrial resection (TMMR) and therapeutic lymphadenectomy (tLNE) are two surgical interventions used to treat early cervical cancer. They are both based on the ontogenic cancer field model and have exhibited good locoregional control rates without adjuvant chemoradiation in a unicentric setting. This study, published in the Journal of Gynecologic Oncology, sought to provide prospective, multicentric...
Novel HPV Nanovaccine Therapy for Cervical Cancer
Treatment for advanced cervical cancer is limited, but the therapeutic HPV vaccine shows promise as a possible treatment option. In this study, published in Biomaterials, researchers constructed a novel HPV nanovaccine and tested its ability to inhibit cervical cancer progression in mice. This HPV vaccine therapy is novel because it combines nanotechnology and photodynamic therapy, which...
HeLa Cells Study Supports Novel Cervical Cancer Treatment
Recent findings have shown that neuropeptide substance P (SP) regulates many tumor-related processes via the neurokinin-1 receptor (NK1R). This study, published in Molecular Biology Reports, used HeLa cells to analyze the relevance of the SP/NK1R system in the pathogenesis and treatment of cervical cancer. Ultimately, it was found that SP increased HeLa cell proliferation while treatment...
A Meta-Analysis of Cervical Cancer Screening Methods
Observational studies have shown a reduction in invasive cervical cancer incidence and mortality thanks to screening programs that use cervical cytological testing. Moreover, randomized controlled trials have shown that cytological testing plus hrHPV testing (co-testing) further reduces invasive cervical cancer incidence. The current guidelines recommend three main screening options: cytological testing, standalone hrHPV testing, and...
Global Perspectives: Is Thyroid Cancer Overdiagnosed?
Although thyroid cancer incidence rates have increased globally, mortality rates have remained low and stable. This pattern may be the result of overdiagnosis. This article, published in The Lancet Diabetes & Endocrinology, analyzes the distribution of thyroid cancer incidence and mortality rates from 2020 to better understand the disease’s epidemiological status. The researchers gathered age-standardized incidence...