November 9, 2022

Acupuncture does not appear to have an immunological effect on the Th1–Th2 imbalance; however, acupuncture treatment reduces levels of eotaxin and other nonspecific pro-inflammatory cytokines in patients with seasonal allergic rhinitis. As a supplementary and integrative medical therapy, acupuncture targets specific acupoints to enhance the treatment of various disorders. As acupuncture is a relatively risk-free...

Topical or nasal probiotics are not a good choice for treating allergic rhinitis. Topical probiotics have been proposed as a therapeutic alternative for allergic rhinitis because they might influence the immune response towards a type-1 non-allergic profile. This randomized placebo-controlled crossover trial, published in Clinical & Experimental Allergy, aimed to determine whether a topical/nasal probiotic...

Benralizumab is effective in treating eosinophilic asthma. It also improves the quality of life of individuals with poorly controlled asthma. Breathlessness, recurrent exacerbations, and decreased quality of life are prevalent in individuals with severe asthma despite high-dose corticosteroids. The hallmarks of severe eosinophilic asthma include eosinophilic airway infiltration, inflammation, blockage, or constriction. Benralizumab, an anti-IL-5Ra,...

With a minimal incidence of amyloid recurrence in the cardiac allograft, cardiac transplantation is well tolerated, increases functional ability, and lengthens survival in patients with ATTR-CM, according to a 30-year retrospective study. ATTR-CM should be included in the list of transplantation indications. Cardiomyopathy caused by transthyretin amyloidosis cardiomyopathy (ATTR-CM) is progressive and fatal. Patients with...

In patients with Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM), tafamidis was associated with a lower rate of CV-related hospitalizations and a shorter stay. Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is an underdiagnosed disease characterized by deposits of improperly folded transthyretin amyloid fibrils, resulting in end-organ dysfunction. ATTR-CM patients present with symptoms of invasive cardiomyopathy and heart failure necessitating expensive...

Emboli are a common complication of amyloid transthyretin cardiomyopathy (ATTR-CM). This study found that the CHA2DS2-VASc score is not useful in predicting embolic events in ATTR-CM patients with or without AF, and that VKAs and DOACs are equally effective in preventing embolism, in this scenario. Transthyretin amyloid cardiomyopathy (ATTR-CM) is an infiltrative illness with a...