December 23, 2022

Missing School Affects Wellbeing in Pediatric Sickle Cell Disease

Children with sickle cell disease have a poorer quality of life compared to their peers and tend to miss more school because of pain and hospitalizations. As a result, their treatment should be focused on improving quality of life.  Sickle cell disease (SCD) is a genetic blood disorder characterized by the sickled shape of red...

Lipid Imbalances in Children with Sickle Cell Disease

People with sickle cell disease (SCD) are more likely to have cholesterol and lipid imbalances, which can increase the risk of serious SCD complications. A recent study found new biomarkers associated with SCD in a cohort of pediatric patients. Sickle cell disease (SCD) commonly occurs in tandem with dyslipidemia. Dyslipidemia increases a patient’s risk for...

Insights on Social Determinants of Health in Sickle Cell Disease

Social determinants of health continue to lead to health disparities in patients with sickle cell disease. Socioeconomic status, neighborhood and community culture, and healthcare access all impact health outcomes, but clinicians can leverage this knowledge to make informed decisions with their patients. Social determinants of health (SDoH) are the environmental factors affecting a person’s wellbeing....

Genetic Cures for Sickle Cell Disease on the Horizon

Sickle cell disease requires constant symptom management. Current treatments attempt to mitigate symptoms, but new genetic approaches introduce a potential to cure the disease at its source. Sickle cell disease (SCD) is an inherited disorder caused by a single point mutation in the hemoglobin beta gene resulting in sickle-shaped red blood cells that fail to...

In Favor of Comprehensive Care for Sickle Cell Disease

Given the vulnerable populations affected by sickle cell disease (SCD), patients benefit from comprehensive, multidisciplinary care teams. This review found financial advantages to comprehensive care by reducing the costs associated with acute visits, such as hospitalizations. Despite advances in therapies for sickle cell disease (SCD), economic challenges still prevent health care providers from adopting comprehensive,...

Hesperidin (HSP) As a Potential Alternative Treatment for Cancer 

Hesperidin is a plant chemical found in citrus fruits, such as oranges, grapefruit, lemon, and tangerines, that may be taken as a dietary supplement. A study found that hesperidin (HSP) may be an effective anticancer treatment. In the medical community, cancer has grown to be a challenging concern due to the nature of the disease....

Gastric Cancer Continues to be  Common Among Puerto Rican Hispanics 

There are differences in gastric cancer incidence and death among ethnic/racial groupings, according to reports. A study in 2022 found that, despite the general decline in prevalence among other racial/ethnic groups, gastric cancer remains a frequent malignancy among Puerto Rican Hispanics. Disparities exist in the overall incidence of gastric cancer among racial and ethnic groups...

Remission and Recurrence of ADHD: A Longitudinal Study

The current understanding of ADHD assumes that many children with ADHD outgrow it by adulthood, but this longitudinal study shows that remission and recurrence are common in most children as they age. It is currently estimated that childhood attention deficit hyperactivity disorder (ADHD) remits in adulthood in around 50% of cases. However, this conclusion is...

Novel Techniques for Identifying Non-Stimulant ADHD Therapeutics

This article describes a new way of identifying possible non-stimulant ADHD therapeutics, which can have fewer side effects than their stimulant counterparts. The most common first-line therapeutic treatment for attention-deficit/hyperactivity disorder (ADHD) is methylphenidate. However, this medication has a number of serious side effects, including weight loss, insomnia, and hypertension. The development of non-stimulant-based therapeutics...
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