January 23, 2023

Impacts of Pregnancy on Breast Cancer Prognosis

Reproductive history can impact breast cancer prognosis and outcomes. Later-life births and having several children is associated with lower survival rates, so regular breast cancer screenings must be emphasized in pregnant women.  Women in low- and middle-income countries are beginning to have fewer children and delaying their first pregnancy. Meanwhile, breast cancer incidence continues to...

Recommendations for Addressing Race-Based Disparities in Breast Cancer Screening

Black women with breast cancer are at an increased risk for negative outcomes and reduced treatment efficacy. Timely, annual screenings can help close the racial disparity and improve prognosis.  Breast cancer presents a unique epidemiological risk to Black women. Black women are more likely to be diagnosed before age 40, and their mortality rates are...

Asthma Medication Reduces Anxiety and Associated Brain Activity

Many people with asthma also suffer from anxiety. A common nasal spray, fluticasone propionate, alleviates asthma and anxiety while improving neural activity and inflammation levels.  Allergic asthma is a common respiratory disease that causes shortness of breath, among other respiratory symptoms. Patients with asthma are more likely to experience anxiety, and these individuals tend to...

Asthma During Pregnancy Needs Targeted Interventions in Underserved Communities

In underserved communities, a lack of educational resources and health access prevent pregnant women with asthma from receiving proper care, but interventions are showing promise. The incidence of asthma in pregnant women is increasing, and those in underserved communities are especially at risk. Women tend to struggle more to control their asthma symptoms during pregnancy,...

Corticosteroid Responsiveness Following Mepolizumab in Severe Eosinophilic Asthma

Oral corticosteroids reduce type 2 inflammatory biomarkers and small-airway obstruction in mepolizumab-treated severe eosinophilic asthma patients. Mepolizumab inhibits IL-5 activity and decreases exacerbation frequency and oral corticosteroid (OCS) maintenance dose in individuals with severe eosinophilic asthma (SEA). Some patients remain dependent on OCS despite use of anti-IL-5 medication, implying persistent corticosteroid-sensitive pathways. This study, published...

ELLIPTA vs. BREEZHALER Dry Powder Inhalers in Patients With Asthma

Patients prefer the ELLIPTA inhaler over the BREEZHALER inhaler. Many asthmatic individuals make mistakes when using inhalers that affect the quantity of treatment they receive. Patients with asthma or chronic obstructive pulmonary disease make fewer crucial errors with the ELLIPTA inhaler than conventional dry powder inhalers after reading the patient information leaflet (PIL). This study,...

Fractional Exhaled Nitric Oxide for the Management of Asthma

FENO-based asthma management in prenatal care is not effective for improving perinatal outcomes. Asthma is one of the most common chronic disorders that affect pregnant women. Asthma affects 8–12% of pregnant women globally, with exacerbations requiring medical intervention affecting 20–45% of these women. Pregnancy-related asthma exacerbations are connected with worse perinatal outcomes. This study was...

BREATHE Asthma Intervention Efficacy and Feasibility

The BREATHE asthma intervention did not reduce respiratory hospitalizations or emergency department (ED) visits. An illness like asthma makes inequalities obvious. Among American Indians and Alaska Natives, it is well known that asthma diagnosis and inadequate control of asthma symptoms are related to lower levels of education, poverty, and minority status. This association may be...

Mild-To-Moderate Acne Is Found in Atopic Dermatitis Patients Using Upadacitinib

Upadacitinib treatment for atopic dermatitis patients has been associated with acne. However, a phase 3 randomized control trial has revealed that the severity of this adverse event is typically mild-to-moderate, and can be effectively managed through the use of topical therapies or left untreated. These findings are reported in the Journal of the American Academy...
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