April 30, 2023

Daratumumab with bortezomib and dexamethasone significantly increased the overall survival in patients suffering from relapsed or refractory multiple myeloma. Daratumumab is a human monoclonal CD38 antibody that poses greater cytotoxicity against multiple myeloma cells than other CD38 antibodies. Adding this drug to the standard treatment regimen for multiple myeloma significantly improves the durability of response...

This phase 1 study demonstrated that chimeric antigen receptor T completely synthetic antigen-binding domain cell therapy is safe and has a durable response in patients with relapsed and refractory multiple myeloma. Relapsed and refractory multiple myeloma (RRMM) is a progressively refractory disease requiring chronic intensive therapy. This phase 1 study aimed to assess the safety...

Obesity and diabetes are more prevalent among Black individuals in both urban and rural settings.  Obesity has been a persistent epidemic in the United States and obese individuals have been known to have a decreased life expectancy compared to the national average. This is even more pronounced in those of African descent, with obese Black...

Heterosexual Black people are twenty times more likely to be diagnosed with HIV than heterosexual White people. The rates of HIV among individuals who practice homosexual sex are well-studied. However, there are limited studies on the prevalence of HIV among heterosexual individuals, which this study aimed to address. In this study, the prevalence of HIV...

Staff Writer: Andre McGowan Skin cancers are more common among the White populace, but morbidity and mortality in skin cancer is higher among Blacks and Hispanics. Skin cancers are among the most common types of cancer in the world. Most skin cancers, such as melanomas and non-melanomas, are more common in the White population, though...

Vitamin D receptor polymorphisms may impact vitiligo susceptibility, and this study analyzes that possibility in various geographic regions as it relates to specific polymorphisms. Although the specific conclusions are still being debated, previous research indicates associations between vitamin D receptor (VDR) polymorphisms and susceptibility to vitiligo. This study, published in the Journal of Cosmetic Dermatology,...

A precise pathogenesis of vitiligo is not yet understood, but this article suggests that it is based on oxidative stress and heightened levels of reactive oxygen species. There are many hypotheses about the pathogenesis of vitiligo, but the most commonly accepted is that of an oxidative stress-induced immune response. This immune response ultimately leads to...