June 5, 2023

Sleep-Disordered Breathing Linked to Medial Temporal Lobe Atrophy in Seniors

Higher sleep apnea severity related to lower medial temporal lobe subregion volumes in amyloid-positive, but not amyloid-negative, individuals. Sleep-disordered breathing (SDB) is associated with medial temporal lobe atrophy in cognitively unimpaired amyloid-positive older adults, according to a study published online May 31 in Neurology. Claire André, Ph.D., from Normandie University in France, and colleagues examined the...

Novel Dialysis Device Safe, Effective for Acute-on-Chronic Liver Failure

No difference seen in 28-day mortality or occurrence of serious adverse events; time to resolution of ACLF significantly faster. The DIALIVE novel liver dialysis device seems safe and has a positive impact for patients with acute-on-chronic liver failure (ACLF), according to a study published online May 31 in the Journal of Hepatology. Banwari Agarwal, M.B.B.S.,...

ASCO: Microbiome Varies for Early-Onset, Late-Onset Colorectal Cancer

Cladosporium sp. was more commonly found in early-onset CRC, while Pseudomonas luteola, Ralstonia sp., Moraxella osloensis occurred more often in late-onset CRC. The microbiome (MB) of patients with colorectal cancer (CRC) varies between those diagnosed with early- or late-onset disease, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from June...

FDA Approves Pfizer RSV Vaccine for Older Adults

CDC expected to meet later in the month to adopt vaccine recommendations for older Americans. Older adults have a second vaccine option for respiratory syncytial virus (RSV) following the U.S. Food and Drug Administration approval of a Pfizer vaccine on Wednesday. The other shot for adults 60 years and older is made by GlaxoSmithKline. It...

Geographic and Socioeconomic Variation in Rare Cancer Incidence and Mortality

The prevalence of rare cancers varies geographically, and this study displays how much of a public health burden these cancers are when looked at collectively. Rare cancers, despite occurring less commonly, account for a quarter of total cancer diagnoses and deaths in the US, Europe, and Australia. Few epidemiological studies have analyzed the distribution and...

Prevalence and Quality of Life Burden of Menopausal Vasomotor Symptoms

A high proportion of European women experience moderate-to-severe menopausal vasomotor symptoms that influence quality of life. The cardinal vasomotor symptoms (VMS) of menopause are hot flashes (HF) and sweats. Up to 80% of women experience VMS during the menopausal transition, with most rating them as moderate to severe. VMS are associated with poor sleep, low...

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