Primary Care

Women with atrial fibrillation and normal baseline cognition had higher risk of disease progression from normal to MCI, MCI to dementia Atrial fibrillation (AF) is associated with increased odds of and with more rapid progression to mild cognitive impairment (MCI) and dementia among women versus men, according to a study published online June 23 in Alzheimer’s...

Both hormonal and non-hormonal therapies are available for treating postmenopausal symptoms. Menopause is the discontinuation of ovarian function and is marked by 12 consecutive months of amenorrhea. It occurs at a median age of 51 years. Postmenopausal symptoms that can be managed include vasomotor symptoms (VMS), vulvovaginal atrophy, sexual dysfunction, dyspareunia, frequent urination, and osteoporosis. ...

Dexamethasone decreases the incidence of docetaxel-induced oral mucositis in patients suffering from breast cancer in a dose-dependent manner. Pharmaceutical formulations containing docetaxel, an effective chemotherapeutic agent for the treatment of breast cancer, commonly lead to the development of oral mucositis (OM). To prevent the fluid retention that is associated with docataxel use in breast cancer...

Psychologically vulnerable breast cancer patients with less education, low social support, low patient activation, and younger age benefited most from nurse navigation intervention. Breast cancer patients with high levels of distress at the time of diagnosis tend to be at risk for physical symptoms and long-term distress. This randomized controlled trial (RCT) evaluated whether breast...

Hypo-fractionated ablative liver radiotherapy is a safe and well-tolerated modality for treating metastatic breast cancer, with excellent local control. Metastasis in breast cancer frequently involves the lungs, bones, and liver. Advancement in the field of radiologic imaging has allowed for the identification of limited metastatic disease in cancer patients. This retrospective cohort described hypo-fractionated liver...

Menopausal symptoms are not associated with physical activity and blood pressure in middle-aged women, and these symptoms are not predictive of changes in cardiometabolic risk. There is an increase in the incidence of metabolic syndrome and cardiovascular disease at the time of menopausal transition, which can be attributed to changes in cardiometabolic risk factors. This...

The consumption of a low-fat, plant-based diet containing decreased dietary advanced glycation end-products aids in reducing the frequency of severe hot flashes in postmenopausal women. Hot flashes in postmenopausal women tend to be associated with a greater risk of developing diabetes and cardiovascular diseases. Changes in the dietary consumption of advanced glycation end-products (AGEs) have...

An increase in vasomotor symptoms, persistent vasomotor symptoms, and a high frequency of vasomotor symptoms may be associated with weight gain among women. The presence of vasomotor and other symptoms during menopause is associated with weight changes in women. Additionally, vasomotor symptoms may impair quality of life, cause sleep disturbances, and hinder memory and concentration. ...

Fezolinetant is a non-hormonal treatment modality that is safe and effective over 52 weeks for treating moderate-to-severe vasomotor symptoms in menopausal women. Menopausal hormone therapy effectively manages vasomotor symptoms in some individuals, but not all women are candidates for hormonal therapy. Fezolinetant is a non-hormonal neurokinin 3 receptor antagonist that works by moderating activity in...