June 13, 2023

Dupilumab Efficacy in Patients with Uncontrolled Moderate-to-Severe Type 2 Asthma

Dupilumab is a human monoclonal antibody that mediates improvement in the clinical outcomes of patients diagnosed with moderate-to-severe type 2 asthma, regardless of the status of allergen sensitization. Dupilumab is defined as a human monoclonal antibody that is implicated in different type-2 anti-inflammatory diseases. The previous study demonstrated that dupilumab decreased severe asthma exacerbation and...

Associations Between Serum Per- and Polyfluoroalkyl Substances and Asthma Morbidity

This study demonstrates the association between greater odds of asthma attacks in the previous 12 months and higher concentrations of PFDA and PFOA in the serum, which was significant for individuals aged 12 to 18 years. Per- and poly-fluoroalkyl substances (PFAS) are chemicals widely utilized in manufacturing and tend to be highly resistant to degradation;...

Asthma Prevalence Increased With High Metabolism Scores for Visceral Fat

This cross-sectional study demonstrated a positive association between the prevalence of asthma and results for the Metabolic Score for Visceral Fat index; however, the relationship is non-linear. There is a negative correlation trend between the prevalence of asthma and the METS-VF index of less than 5.24. The Metabolic Score for Visceral Fat (METS-VF) estimation tool...

Obesity as a Risk Factor for Cancer

This review reveals significant associations between obesity and liver, prostate, breast, and colorectal cancers. Obesity has become a major public health issue over the last few decades. It has been associated with multiple metabolic syndromes and an increased risk of malignancies. Moreover, growing evidence shows that weight loss may lower the risk of developing cancer....

Health Education Program Improves Gastric Cancer Surgery Patients' Supplement Compliance

The 5Ts for Teach-Back method of health education can improve compliance with oral nutritional supplements in post-discharge patients after gastric cancer surgery. Surgery for gastric cancer results in metabolic changes and absorption disorders, leading to worsening nutritional status after discharge. Oral nutritional supplements (ONS) are recommended for malnutrition after tumor surgery; however, studies show poor...

Impacts of Different Environmental Factors on Autoimmunity

This study presents a review of the influence of different environmental factors on autoimmune diseases. The interplay between environmental factors and genetic susceptibility triggers autoimmune disease onset. Risk factors such as Epstein–Barr virus infection and coffee, tobacco, and alcohol consumption have been extensively reviewed. A review in the journal Frontiers in Immunology has focused on...

Rehabilitation Therapy for Multiple Sclerosis

This article reviews treatments for the rehabilitation of multiple sclerosis patients. Multiple sclerosis (MS) is an autoimmune inflammatory disorder that causes demyelination in the central nervous system. Progression of the disease leads to chronic neurological deficits. Professional rehabilitation therapy during the disease course can reduce disability and improve the functional status of MS patients. A...

Neurodegeneration in Multiple Sclerosis

This study presents a review of the neurogenerative mechanisms in multiple sclerosis. Multiple sclerosis (MS) is an autoimmune, inflammatory, and neurodegenerative disease of the central nervous system (CNS). The hallmark of MS is inflammatory demyelinating lesions, impaired recovery of which may lead to permanent neurodegeneration and disability. A study in the journal WIREs Mechanisms of...

Respiratory Syncytial Virus Infection Prevention and Treatment

This study presents a review of the treatment and prevention strategies for respiratory syncytial virus. Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract disease globally, especially in young children. Despite its high prevalence and morbidity, the available therapy is mostly supportive. Recent developments in novel therapies offer hope for reducing...
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