December 14, 2023

High Low-Density Lipoprotein Cholesterol Levels and Early-Onset Vasomotor Symptoms

Higher serum levels of low-density lipoprotein cholesterol are positively related to the risk of early-onset vasomotor symptoms in premenopausal women. The predominant symptoms evident during the menopausal transition are vasomotor symptoms, including night sweats and hot flashes. Long-lasting and severe vasomotor symptoms tend to be associated with obesity, adverse cholesterol levels, high blood pressure, and...

Company Seeks FDA Approval for MDMA as Treatment for PTSD

Medication would be given in concert with talk therapy A California company is asking the U.S. Food and Drug Administration to consider approving MDMA (midomafetamine capsules) as a treatment for posttraumatic stress disorder (PTSD). When announcing the new drug application (NDA) filing on Tuesday, MAPS Public Benefit Corp. noted it has been studying the drug...

Single Dose of mRNA-1345 Vaccine Safe, Effective Against RSV in Seniors

Vaccine efficacy was 68.4 percent against RSV-associated acute respiratory disease; offers protection against subtypes A and B A single dose of mRNA-1345 vaccine is safe and results in lower incidence of respiratory syncytial virus (RSV)-associated disease in older patients, according to a study published in the Dec. 14 issue of the New England Journal of Medicine....

Treatment Modification Common With Second-Line Antidiabetic Meds

Lowest adjusted risk of switching and highest intensification risk for patients prescribed sufonylureas Most patients with type 2 diabetes initiating antidiabetic medication (ADM) experience treatment modification within one year, according to a study published in the December issue of the American Journal of Managed Care. David T. Liss, Ph.D., from the Northwestern University Feinberg School of...

Blacks More Likely to Have Disseminated Manifestations of Lyme Disease

Black patients have significantly longer median time to appropriate antibiotic treatment than Whites Black patients are more likely to be diagnosed with disseminated manifestations of Lyme disease (LD) and experience longer time to appropriate treatment, according to a research letter published online Dec. 12 in JAMA Network Open. Samuel J. Starke, M.D., from the Johns Hopkins...

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