Contributions
Attention-Deficit Disorder, Family Factors, and Oral Health Literacy
Level of oral health literacy (OHL) is associated with signs of ADHD, family income, maternal schooling, and family cohesion and adaptability. The association between oral health literacy (OHL), relationships, and family factors in adolescents with attention-deficit hyperactivity disorder (ADHD) are relatively unclear. Studies suggest that hyperactivity and inattention in ADHD may lead to impairment of...
Ocular Trauma and Attention-Deficit Hyperactivity Disorder in Adults
A recent study that investigated the onset of ADHD-related clinical outcomes in the setting of ocular trauma found that Wender–Utah Rating Scale (WURS) scores were similar in the control and ocular trauma groups. Moreover, ADHD-related clinical outcomes, including higher behavioral problems/impulsivity subscale scores, are related to ocular trauma in outdoor activities. Ocular trauma is an...
A Lack of Clinical Awareness of ATTR-CM
Clinical awareness and early detection of ATTR-CM may be lacking. One study assessed the degree to which there is a lack of awareness among clinicians and offered suggestions on how to resolve it. ATTR-CM, or transthyretin amyloid cardiomyopathy, is a disease that is often misdiagnosed. ATTR-CM presents as a restrictive cardiomyopathy and is associated with...
Assessing the Clinical and Economic Burden of ATTR-CM
Data suggests that patients with transthyretin cardiomyopathy (ATTR-CM) have short survival times and high medical costs. One study assessed the burden of disease and medical costs for patients with ATTR-CM. Transthyretin cardiomyopathy (ATTR-CM) is an underdiagnosed disease with a poor prognosis that generally affects patients over the age of 60. Because of differences in genotype...
Potential Effects of Tafamidis on Reversing Cardiac Remodeling
Patients with the A97S genotype of ATTR-CM may exhibit functional and structural improvements after tafamidis treatment. A recent case study showcased these potential benefits. Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is an under-recognized cause of heart failure. Mutations in the TTR gene are thought to destabilize and change the shape of the protein. Although under-represented in major...
SGLT2 Inhibitors for Transthyretin Amyloid Cardiomyopathy
In patients stabilized on tafamidis, SGLT2 inhibitors may be beneficial for improving outcomes of transthyretin amyloid cardiomyopathy (ATTR-CM). Treatment with dapagliflozin was found to be well-tolerated in patients with ATTR-CM. Transthyretin amyloid cardiomyopathy (ATTR-CM) is a heart disease that can be fatal. In recent years, more and more people have been diagnosed and subsequently hospitalized...
Malaria and Sickle Cell Anemia in Ugandan Children
Patients with sickle cell anemia (SCA) may be protected from severe disease with malaria. However, severe complications, such as severe drops in hemoglobin, may occur in SCA patients with concomitant low-density malarial infection. Sickle cell anemia (SCA) has historically been linked to high levels of childhood mortality in Africa, with malaria playing a significant role....
Oral L-Glutamine for Sickle Cell Disease
L-glutamine is an FDA-approved treatment for sickle cell disease. One study explored the potential benefits and mechanism of action of L-glutamine in sickle cell disease patients. Leukocytosis is common in sickle cell disease (SCD) in the absence of infection and is a predictor for increased risk of stroke, acute chest syndrome, and mortality. Oral L-glutamine...
Supplementation for Pain Prevention and Treatment of SCD
Supplementation with omega-3 or vitamin D may be useful for preventing and treating pain in patients with SCD. One study assessed the effects of supplementation in conjunction with standard therapy. A common clinical feature present in sickle cell disease (SCD) is pain caused by the distortion of red blood cells and the subsequent blocking of...