Contributions
Cemiplimab Prolongs Survival in Recurrent Cervical Cancer
For patients with recurrent cervical cancer after first-line platinum-containing chemotherapy, survival is significantly longer with cemiplimab than with single-agent chemotherapy, according to a study published in the Feb. 10 issue of the New England Journal of Medicine. Krishnansu S. Tewari, M.D., from the University of California in Irvine, and colleagues enrolled patients with recurrent cervical cancer...
Study Finds No Ties Between Youth Tackle Football, Brain/Behavioral Issues
Many parents struggle with the decision to let their kids play tackle football or other contact sports due to the risk of concussions and long-term brain diseases that may occur with repeated head blows. Now, new research suggests that head trauma and concussions aren’t linked to problems with memory, attention, processing speed, or behavior in 9- to 12-year-olds who...
Poll Finds Most Parents Would Use CBD to Treat a Child — Is That Wise?
Cannabidiol (CBD) products are wildly popular among older adults for treating chronic pain and anxiety, and a new poll suggests that nearly three-quarters of U.S. parents think CBD might also be a good option for their kids when other meds don’t work. On the other hand, more than that — 83% — think CBD products should be...
Neurodevelopmental Disorders for Most Children Born Before 24 Weeks
Most children born before 24 weeks have neurodevelopmental disorders and/or somatic diagnoses in childhood, according to a study published in Acta Paediatrica. Eva Morsing, Ph.D., from Lund University in Sweden, and colleagues examined childhood diagnoses in children born extremely preterm before 24 weeks of gestation using data retrieved from national Swedish registries from 2007 to 2018....
Few Foods Could Be Recipe for Easing ADHD Symptoms
Can a highly restrictive eating regimen of just a few foods ease the classic symptoms of attention deficit hyperactivity disorder (ADHD) in kids? New research suggests that short-term nutritional intervention, which tests whether certain foods are a trigger for ADHD symptoms through the process of elimination, might make a difference. ADHD can result in inattentiveness, hyperactivity, and...
Structural Brain MRI Measures Compared for Youth With, Without ADHD
Children aged 9 to 10 years with attention-deficit hyperactivity disorder (ADHD) differ modestly from their unaffected peers in structural brain MRI measures, according to a study published in The Lancet Psychiatry. Joel Bernanke, M.D., from New York State Psychiatric Institute in New York City, and colleagues conducted a cross-sectional study using baseline demographic, clinical, and neuroimaging...
Early-Life Daycare Tied to Worsening Behavior in Kids
The more time kids spend in daycare, the greater their risk for problem behaviors in primary school, according to a Swiss study. But, parents can take heart. The study also found that such problems generally disappear by the end of primary school. “It’s possible that external childcare may lessen the strength of child-parent attachment and...
Prenatal Opioid Exposure Increases Risk for Childhood ADHD
Prenatal opioid exposure is associated with a significantly higher risk for subsequent attention-deficit/hyperactivity disorder (ADHD) and carries a higher risk than exposure to other substances, according to a study published in JAMA Network Open. Henri M. Garrison-Desany, from the Johns Hopkins Bloomberg School of Public Health in Baltimore, and colleagues estimated the aggregate burden of...
Treating Sickle Cell Disease With Etavopivat
This study, published in the Journal of Pharmacology and Experimental Therapeutics, evaluates the response of both non-human primates and healthy human subjects to etavopivat. Etavopivat is a small molecule activator of the glycolytic enzyme erythrocyte pyruvate kinase. It is being developed to treat sickle cell disease (SCD) and is hypothesized to work via multiple mechanisms that increase...