Cardiovascular Risk Management

The trough plasma concentration of atorvastatin metabolites has a moderate correlation with a decrease in the levels of low-density lipoprotein cholesterol, according to the results of a randomized double‐blind crossover trial. Atorvastatin metabolites hold potential value in monitoring and optimizing the drug dosage for optimal clinical efficacy.    Statins form the standard treatment in the primary...

Rosuvastatin and atorvastatin were comparable in terms of all-cause death, coronary revascularization, myocardial infarction, or stroke at 3 years of intervention in a randomized prospective trial. However, rosuvastatin administration was related to comparatively lower levels of low-density lipoprotein cholesterol and a higher risk for cataract surgery and antidiabetic treatment. Statins are known to be effective...

Compared to a healthy omnivorous diet, a healthy vegan diet was associated with improved cardiometabolic parameters, including decreases in low-density lipoprotein cholesterol levels, fasting insulin levels, and body weight in an 8-week study of identical twins. Dietary patterns with high plant-based and low animal-based foods are associated with positive health and environmental outcomes. A well-formulated...

The 3-year composite of death, myocardial infarction, coronary revascularization, and stroke outcomes were comparable between treat-to-target and high-intensity statins in coronary artery disease patients in a recent randomized trial. Coronary artery disease (CAD) is associated with an increased risk for adverse cardiovascular events. Studies have recommended statin therapy for reducing the levels of low-density lipoprotein...

But increase in cardiovascular disease mortality seen after more than 20 years of follow-up among older women For postmenopausal women, calcium and vitamin D (CaD) supplements may reduce cancer mortality and increase cardiovascular disease (CVD) mortality after more than 20 years of follow-up, according to a study published online March 12 in the Annals of Internal...

Yet prescription rates remain substantially lower than that seen for other guideline-recommended cardiometabolic therapies Barriers for proprotein convertase subtilisin/kexin type 9 inhibitor (PCSK9i) use persist for cholesterol management, according to a research letter published online Feb. 16 in Circulation: Cardiovascular Quality and Outcomes. Diane E. MacDougall, from the Family Heart Foundation in Fernandina Beach, Florida, and...

Regular physical activity linked to reduced risk for all-cause mortality in women and men, with greater reduction for women Sex-specific differences are seen in the association between leisure-time physical activity and all-cause and cardiovascular death, according to a study published in the Feb. 27 issue of the Journal of the American College of Cardiology. Hongwei Ji,...

Improvement seen in cognition and general health; changes also seen in blood vessel efficiency and cortical thickness of temporal cortex Bariatric surgery (BS) is associated with cognitive benefits two years after surgery, according to a study published online Feb. 9 in JAMA Network Open.[spacer height=”20px”] Emma Custers, from Radboud University Medical Center in Nijmegen, Netherlands,...

Panel concentrated on how to ensure the accuracy of pulse oximeters for all skin tones before they reach drugstore shelves On Friday, a U.S. Food and Drug Administration advisory panel addressed the ongoing issue of less accurate readings from pulse oximeters when used by individuals with darker skin. During its daylong meeting, the FDA Anesthesiology and...