Cardiovascular Risk Management

An analysis of cohort data from the Multi-Ethnic Study of Atherosclerosis database found that elevated remnant cholesterol is a residual risk factor for aortic valve calcium progression, regardless of the conventional cardiovascular risk factors. Aortic valve calcium (AVC) is associated with the development of calcific aortic valve disease, which is one of the leading causes...

Patients shifting from an oral regimen to injectable cabotegravir plus rilpivirine demonstrated a significant improvement in total cholesterol/high-density lipoprotein cholesterol in a recent retrospective cohort study; however, there were no significant changes in inflammatory biomarkers. Long-acting cabotegravir plus rilpivirine, administered via injection into the gluteus muscle, has a higher satisfaction rate compared to antiretroviral therapy...

C-reactive protein is negatively correlated with high-density lipoprotein in patients with dry age-related macular degeneration and may serve as an early disease predictor, according to the results of a retrospective study. The development of age-related macular degeneration (AMD) is associated with several risk factors, such as abnormal levels of lipid analytes, the patient’s age, and...

First-trimester dyslipidemia in pregnant women with subclinical hypothyroidism is associated with an increased risk of adverse pregnancy outcomes, according to a recent cohort study. Subclinical hypothyroidism is associated with dyslipidemia and may have adverse pregnancy outcomes. This thyroid disorder is common during pregnancy, increasing the risk for small for gestational age infants, preterm birth, and...

High lipoprotein-associated phospholipase A2 activity is associated with an increased risk for cardiovascular death and major adverse cardiovascular events in patients undergoing maintenance hemodialysis, facilitating the identification of patients at a greater cardiovascular mortality risk, according to the results of a recent prospective cohort study. Dyslipidemia is a common complication among chronic kidney disease patients...

Mediterranean-style and anti-inflammatory diets tied to decreased arterial stiffness An obesogenic dietary pattern in childhood is associated with increased arterial stiffness in adolescence, according to a study published online Jan. 5 in the British Journal of Nutrition. Genevieve Buckland, Ph.D., from the University of Bristol in the United Kingdom, and colleagues examined the relationship between childhood...

Initiators of statins aged 75 years or older had higher mean percentage reduction than those younger than 50 years. For older versus younger adults, low- to moderate-intensity statins are associated with a greater reduction in low-density lipoprotein cholesterol (LDL-C), according to a study published online Aug. 1 in the Annals of Internal Medicine. Giulia Corn, Ph.D.,...

Recent research analyzed the association of modifiable risk factors with cardiovascular disease and death in a global cohort. Modifiable risk factors such as body mass index (BMI), systolic blood pressure (SBP), non-high-density lipoprotein (non-HDL) cholesterol level, smoking, and diabetes are associated with cardiovascular disease (CVD); however, data regarding their impact varies according to the study...

Those randomly assigned to receive ACE inhibitor had increased risks for stroke mortality, fatal and nonfatal hospitalized stroke versus diuretic group For patients with hypertension and at least one other coronary heart disease risk factor, cardiovascular disease (CVD) mortality is similar for those receiving a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting enzyme (ACE)...