Heart Health

A recent study examined the confounding effect of mortality on the frequency of CV-related hospitalization in patients in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT). The impact of tafamidis on CV-related hospitalization was underestimated in the ATTR-ACT, according to researchers. Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive disease caused by the buildup of amyloid...

Clinical awareness and early detection of ATTR-CM may be lacking. One study assessed the degree to which there is a lack of awareness among clinicians and offered suggestions on how to resolve it. ATTR-CM, or transthyretin amyloid cardiomyopathy, is a disease that is often misdiagnosed. ATTR-CM presents as a restrictive cardiomyopathy and is associated with...

Data suggests that patients with transthyretin cardiomyopathy (ATTR-CM) have short survival times and high medical costs. One study assessed the burden of disease and medical costs for patients with ATTR-CM. Transthyretin cardiomyopathy (ATTR-CM) is an underdiagnosed disease with a poor prognosis that generally affects patients over the age of 60. Because of differences in genotype...

Patients with the A97S genotype of ATTR-CM may exhibit functional and structural improvements after tafamidis treatment. A recent case study showcased these potential benefits. Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is an under-recognized cause of heart failure. Mutations in the TTR gene are thought to destabilize and change the shape of the protein. Although under-represented in major...

In patients stabilized on tafamidis, SGLT2 inhibitors may be beneficial for improving outcomes of transthyretin amyloid cardiomyopathy (ATTR-CM). Treatment with dapagliflozin was found to be well-tolerated in patients with ATTR-CM. Transthyretin amyloid cardiomyopathy (ATTR-CM) is a heart disease that can be fatal. In recent years, more and more people have been diagnosed and subsequently hospitalized...

Patients with heart failure typically experience high rates of morbidity and mortality, as well as increased healthcare costs. Disparities in risk factors and treatment strategies for patients with heart failure exist and need to be addressed by the healthcare community. Disparities in heart failure risk factors and treatment methods span across racial and ethnic groups....

Researchers investigated geographic disparities in heart failure outcomes in states with the highest and lowest life expectancies. Disparities in heart failure mortality and incidence, as well as the decline in survival rates of heart failure patients, emphasize the need for appropriate treatment strategies. Geographic disparities in life expectancy (LE) exist in the United States, which...

This study, published in Diabetes Care, provides an analysis of sex disparities in cardiovascular health among participants with diabetes. Specifically, the authors analyzed the results of cardiovascular outcome trials. The data were obtained from random placebo-controlled studies investigating the relationship between various diabetes medications and cardiovascular health. All participants had type 2 diabetes.  Five cardiovascular...

Hispanics and blacks are most likely to stay home if experiencing medical emergencies, like a heart attack or stroke, to avoid the risk of contracting COVID-19 at the hospital, according to a poll released by the American Heart Association (AHA). The Harris Poll conducted the online survey of 2,050 adults on behalf of the AHA...