Compared to normal-weight children, obese or overweight children demonstrated lower concentrations of asymmetric dimethylarginine, γ-aminobutyric acid, and symmetric dimethylarginine, along with higher concentrations of glutamate, threonine, carnitine, and acetylcarnitine. The underlying biological responses that contribute to the current obesogenic environment in early life remain poorly understood. Despite the worldwide increase in childhood obesity, the pathophysiological...