Oncology

This study found a positive correlation between risk for colorectal cancer and early life body size owing to the retention of large body size into adulthood. Childhood obesity has an increasing prevalence across most geographic regions and serves as a major public health challenge globally. A Mendelian randomization study suggested a positive correlation between the...

A center-based cardiac rehabilitation program has greater adherence and satisfaction rates compared to community-based exercise training administered to cancer survivors with cardiovascular risk, according to this study. Both cardiovascular mortality and cardiovascular risk factors pose a significant burden on healthcare. A randomized controlled trial assessed the adherence, safety, and satisfaction of a center-based cardiac rehabilitation...

Consistent consumption of raw carrots is associated with protection against lung cancer, leukemia, pancreatic cancer, and large bowel cancer. Various cohort studies have demonstrated the role of consistent consumption of fruits and vegetables in reducing the risk of various types of cancer. Carrots are a major source of falcarinols, which have been shown to inhibit...

Cancer patients did not experience a reduced psychological burden, including depression, fatigue, and anxiety, after being exposed to video sequence-based interventions. Cancer patients are likely to experience psychological symptoms and require psychological support, particularly during the COVID-19 pandemic. A randomized controlled trial investigating the outcomes of eHealth video sequence-based interventions demonstrated that video interventions were...

Self-administered passive sound interventions are feasible among cancer patients, with positive fatigue and social functioning outcomes. Besides morbidity and mortality, cancer substantially affects the quality of life of cancer patients. Music therapy has gained significant traction among various interventions developed for improving the emotional and physical well-being of cancer patients. This randomized controlled trial demonstrated...

Virtual reality is a potential alternative for pain prevention in bone marrow biopsy, as it is well-tolerated and associated with high patient and healthcare provider satisfaction. Bone marrow biopsy is associated with high levels of pain, despite local analgesia using lidocaine. Inhalation of the mixture of nitrous oxide/oxygen (MEOPA) is relatively easy to use and...

OBI-999 monotherapy was determined to be well-tolerated and safe for patients with advanced solid tumors; however, it was associated with dose-limiting non-cumulative neutropenia. OBI-999 is a new antibody–drug conjugate comprising the Globo H-targeting antibody, OBI-999, combined with cytotoxic monomethyl auristatin E (MMAE). This study demonstrated that the drug was well-tolerated in patients with advanced solid...

Reminiscence therapy significantly affects cancer-related symptoms, including depression and anxiety, and is also useful in improving self-esteem, quality of life, and self-hope. Cancer survivors exhibit significant psychological and physical changes owing to a long course of treatment. Reminiscence therapy has been used to treat psychological disorders, including anxiety and depression. A systematic review and meta-analysis...

Neurofeedback training for cancer patients improves affective symptoms but does not influence perceived cognitive impairment. Neurofeedback, also known as EEG biofeedback, is an established therapeutic intervention that enables individuals to address changes in their brainwaves so as to influence their cognitive-emotional state. This randomized controlled trial evaluated the role of neurofeedback training in the psycho-oncological...