Oncology

Systemic alterations brought on by exercise can potentially decrease disease progression in men with advanced prostate cancer. Physical activity has been shown to improve physical function and the results of supportive treatment for cancer patients, particularly those with advanced disease. In addition, prostate cancer patient epidemiological studies consistently demonstrate a positive correlation between increased physical...

The electronic nose is a promising diagnostic tool with high accuracy for the identification of prostate cancer in urine samples. The gold standard for the diagnosis of prostate cancer is the prostate biopsy, with a detection rate of 21.0%–48.5% for any prostate cancer. Prostate biopsy is associated with a high rate of missed diagnoses of...

Decision-making in localized prostate cancer treatments is informed by functional and QoL outcomes over six years, without any adverse outcomes on mental and physical QoL. Radical localized prostate cancer treatments have positive oncological outcomes. Quality of life (QoL) and functional outcomes are assessed using patient-reported outcome measures (PROMs). This study aimed to analyze the QoL...

Biological mechanisms associated with prostate cancer risk and obesity form the basis for the development of prevention and treatment strategies for prostate cancer. Prostate cancer is the second most common cause of cancer-related death in the United States male population. Obesity has a prevalence of 36.6% in the adult male population in the US. Obesity...

As additional treatments for painful crises in juvenile sickle cell disease, vitamin D and omega-3 could result in overall cost savings and therapeutic benefits. Painful crises are the most prevalent complication of sickle cell disease (SCD). Omega-3 and vitamin D were found to have a possible therapeutic effect on painful crises. This research was published...

In terms of pain relief, the ketamine-based regimen was not determined to be superior to the morphine-based regimen. Nevertheless, ketamine therapy was related to a considerable decrease in cumulative opioid dose. Sickle cell disease (SCD) is an inherited hematologic illness in which deoxygenated hemoglobin polymerizes, causing red blood cells to assume a sickle-like shape. These...

iCanCope is a digital pain self-management platform that helps patients and caregivers easily manage pain episodes. It has been shown to help reduce the frequency and severity of SCD pain episodes. In addition, it can also help improve the quality of life for both patients and caregivers. Sickle cell disease (SCD) is a group of...

Patients with sickle cell anemia (SCA) may be protected from severe disease with malaria. However, severe complications, such as severe drops in hemoglobin, may occur in SCA patients with concomitant low-density malarial infection. Sickle cell anemia (SCA) has historically been linked to high levels of childhood mortality in Africa, with malaria playing a significant role....

L-glutamine is an FDA-approved treatment for sickle cell disease. One study explored the potential benefits and mechanism of action of L-glutamine in sickle cell disease patients. Leukocytosis is common in sickle cell disease (SCD) in the absence of infection and is a predictor for increased risk of stroke, acute chest syndrome, and mortality. Oral L-glutamine...