June 12, 2023

Safety and Immunogenicity of Respiratory Syncytial Virus Prefusion F Vaccine

Respiratory syncytial virus prefusion F candidate vaccine is safe and can boost humoral and cell-mediated immune responses in older adults. Respiratory syncytial virus (RSV) causes respiratory tract infections with seasonal peaks. Natural immunity is incomplete and short-lived. Severe RSV-associated lower respiratory tract disease (RSV-LRTD) occurs in older adults (mostly ≥60 years), especially with underlying medical...

Bladder Cancer Treatment May Lower Risk for Alzheimer and Related Dementias

Greater effect seen for patients aged 70 years and older at time of bacillus Calmette-Guerin vaccination. The bacillus Calmette-Guerin (BCG) vaccine is associated with a significantly lower rate and risk for Alzheimer disease and related dementias (ADRD) among patients with bladder cancer, according to a study published online May 19 in JAMA Network Open. Marc S....

AI Can Estimate Best-Corrected Visual Acuity With Diabetic Macular Edema

Mean absolute error was within 10 letters of actual best-corrected visual acuity. Artificial intelligence (AI)-determined best-corrected visual acuity (BCVA) from remotely obtained fundus photographs is feasible for evaluating diabetic macular edema (DME), according to a study published online June 8 in JAMA Ophthalmology. William Paul, from the Johns Hopkins University School of Medicine in Baltimore, and...

Recommendations Updated for Nonhormonal Management of Vasomotor Symptoms

Cognitive behavioral therapy, clinical hypnosis, SSRIs/serotonin-norepinephrine reuptake inhibitors recommended based on level I evidence. In a position statement issued by the North American Menopause Society and published online June 1 in Menopause, updated recommendations are presented for the nonhormonal management of menopause-associated vasomotor symptoms. Chrisandra L. Shufelt, M.D., from the Mayo Clinic in Jacksonville, Florida, and...

Preterm Birth, Low Birth Weight Linked to Lower Incidence of Fracture

Very preterm newborns, those with low birth weight had lower incidence of fractures during mean follow-up of 10 years. Very preterm infants and those with low birth weight have a lower incidence of fractures during childhood, according to a study published online May 23 in the Journal of Bone and Mineral Research. Ilari Kuitunen, M.D., Ph.D.,...

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