Tracey Roizman

Beta-sitosterol supplements seem to be most appropriate for younger men with minimal symptoms who wish to avoid clinical drug regimens for benign prostatic hyperplasia treatment, according to the findings of a recent literature review. Herbal supplements containing plant sterols, vitamins, and minerals are widely used to enhance prostate health. Beta-sitosterol often forms the most abundant...

Radiomics models based on automatic segmentation of pretreatment apparent diffusion coefficient maps showed promise for predicting the biochemical recurrence of advanced prostate cancer in a recent study. Many prostate cancer (PCa) patients experience biochemical recurrence (BCR) during treatment. Early BCR detection is essential for timely intervention to limit disease progression and improve survival. Radiomics is...

The presence of multifocal positive surgical margins after robotic radical prostatectomy was associated with mortality in patients with adverse clinical and pathological characteristics in a retrospective cohort study. Positive surgical margins (PSMs) represent an adverse feature in prostate cancer patients undergoing radical prostatectomy (RP). PSMs are common post-RP and found in 6–40% of patients. Although...

Aberrant expression of various glycolytic enzyme genes is significantly associated with prostate cancer progression and survival outcomes, according to a recent systematic analysis. Prostate cancer (PCa) is the second-leading cause of cancer death in men. Recent studies showed that alterations in metabolic pathways are involved in PCa development and progression.  A study in the American...

Transperitoneal and extraperitoneal approaches to three-dimensional laparoscopic radical prostatectomy have similar clinical outcomes, according to a recent retrospective study. Radical prostatectomy is among the best treatments for localized prostate cancer. Three-dimensional laparoscopic radical prostatectomy (3D LRP) has two main surgical approaches, namely 3D extraperitoneal LRP (3D ELRP) and 3D transperitoneal LRP (3D TLRP). There is...

The fatty acid-binding protein 5 inhibitor SBFI-103 can potentially eliminate drug-resistant prostate cancer cells at a well-tolerated dose. Prostate cancer (PCa) treatment faces challenges due to the lack of effective targets, as initial success with androgen receptor blockade gives way to drug resistance and lethal relapse of the disease. Research has shown that lethal recurrent...

Vaccine effectiveness wanes after one dose but remains relatively unchanged over four years after two doses Two doses of recombinant zoster vaccine (RZV) are effective against herpes zoster (HZ), with the vaccine effectiveness (VE) of two doses waning little over four years of follow-up, according to a study published online Jan. 9 in the Annals of...

Diagnosis of bipolar disorder increased odds of mortality more than history of smoking or age 60 years or older Bipolar disorder (BD) increases the odds of mortality more than a history of smoking, according to a study published in the December issue of Psychiatry Research. Anastasia K. Yocum, Ph.D., from the University of Michigan in Ann...

Disparities no longer seen once a neuraxial catheter is in situ among those undergoing intrapartum cesarean delivery Racial disparities in the rates of general anesthesia use persist among patients undergoing cesarean delivery, according to a study published online Jan. 9 in JAMA Network Open. Caroline Leigh Thomas, M.D., from the University of Chicago Medical Center, and...