Tracey Roizman

Autologous hematopoietic stem cell transplantation was found to be superior to alemtuzumab in controlling disease activity and improving cognition and quality of life in multiple sclerosis in a recent  observational cohort study. Multiple sclerosis (MS) is an autoimmune neurological disease affecting approximately 2.8 million people worldwide. Autologous hematopoietic stem cell transplantation (aHSCT) is a highly...

A recent case–control study found that HLA-DR15 and MERTK genotypes influenced the proportions of MERTK-expressing monocytes in multiple sclerosis. Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous system. Genetic and environmental factors are implicated in the etiology of MS. HLA-DRB1*15:01 (DR15) and MERTK are two genes associated with the risk for...

Women had low levels of several vitamins that can be obtained in over-the-counter supplements Many women appear to have marginal or low concentrations of folate, riboflavin, vitamin B12, or vitamin D during preconception, according to a study published online Dec. 5 in PLOS Medicine. Keith M. Godfrey, Ph.D., from University of Southampton in the United Kingdom,...

Replacement of biomass fuel with LPG does not reduce the incidence of severe pneumonia among infants An intervention that replaces biomass fuel (e.g., wood, dung, or agricultural crop waste) with liquefied petroleum gas (LPG) for cooking does not affect the incidence of severe pneumonia among infants, according to a study published in the Jan. 4...

Authors say future work should focus on determining if transfers are needed Patients with Alzheimer disease and other related dementias (ADRD) are less likely to receive intensive care unit admission or procedures after transfer from an emergency department to a tertiary care hospital, according to a study recently published in Alzheimer’s & Dementia: Diagnosis, Assessment &...

Higher estimated risk for clonal hematopoiesis of indeterminate potential seen for those with ischemic but not hemorrhagic stroke Radon exposure is associated with an increased risk for clonal hematopoiesis of indeterminate potential (CHIP) among postmenopausal women with ischemic stroke, according to a study published online Jan. 3 in Neurology. Kurtis M. Anthony, M.P.H., from the Gillings...

A retrospective Medicaid data analysis notes delays in initiating disease-modifying anti-rheumatic drug therapy in Black vs. White patients with psoriatic arthritis.  Psoriasis is an autoimmune disorder with highly varying presentations. Although skin lesions are present in most cases of psoriasis, epidemiological data suggests that 30% of those affected by psoriasis will ultimately develop psoriatic arthritis...

Based on Kaplan–Meier analysis, the survival time for infliximab is comparatively longer than that for adalimumab; however, there are no significant differences between the two drugs based on retention rate, with their efficacy diminishing over time. Psoriasis can be described as a chronic immune-mediated disorder that requires lifelong treatment. A drug’s survival and retention rates...

As the aesthetics industry continues to grow, clinicians must educate themselves regarding appropriate treatments and protocols for patients with skin of color to prevent adverse reactions. There is a lack of information for Fitzpatrick skin types IV–VI, and increasing knowledge and skills is imperative for safe and effective treatments. With exponential growth in the aesthetics...