Alopecia

Patients with palmoplantar pustulosis (PPP) have an overlapping comorbidity profile with patients with psoriasis vulgaris, according to a study published in JAMA Dermatology. Dong Hyo Kim, M.D., from the Seoul National University College of Medicine in South Korea, and colleagues conducted a nationwide population-based cross-sectional study involving Korean patients diagnosed with PPP, psoriasis vulgaris, or...

In a recent editorial, the authors raise concern that baricitinib, the first drug approved to treat alopecia areata, was not adequately tested in people of color. Additionally, its higher cost may further contribute to health disparities. The introduction of baricitinib can be described as a game-changer for the treatment of alopecia areata (AA). Until now,...

One of the most extensive epidemiological investigations in the last five decades regarding alopecia areata prevalence and incidence in the United States shows that the burden of the condition is rising, disproportionately affecting females and people living in the Northeast. To overcome health disparities and fight diseases effectively, it is vital to understand the prevalence...

A new study found that Blacks and Hispanics are much more likely to be affected by alopecia areata than Whites. The study also found that, due to a lack of access to healthcare, people from lower education and income groups are less likely to be diagnosed with alopecia areata. Alopecia areata (AA) is an autoimmune...

A recent study provides unique insights into alopecia areata presentation in Hispanic/Latinx patients. It found that comorbidities and nutritional deficiencies were common in the group.  To understand health disparities, it is vital to characterize the unmet needs of alopecia areata (AA) patients from various ethnic groups. This retrospective study, published in the Journal of the...

A retrospective study reports that when enrolling patients for alopecia areata clinical trials, Blacks are likelier to fail initial screening and have higher withdrawal or early termination rates.  Hispanic and Black people have a higher incidence of alopecia areata (AA) during their lifetimes compared to White people. However, disease etiology and pathology differences between various...

Medically reviewed by Dr. Shani Saks, D.O. on Sept. 12, 2023 The pathogenesis of stress-induced alopecia areata involves apoptotic and autoimmune pathways that may interact with one another in the development of the disease, serving as potential therapeutic targets. Alopecia areata is an autoimmune dermatological condition that leads to reversible hair loss in the form of patches....

Medically reviewed by Dr. Shani Saks, D.O. on Sept. 10, 2023 Oral Janus kinase inhibitors such as brepocitinib, baricitinib, deuruxolitinib, and ritlecitinib are effective for the treatment of alopecia areata, causing significant regrowth of hair with only mild to moderate adverse effects. Alopecia areata is characterized by the immune-mediated loss of hair in non-cicatricial patches. While...

Medically reviewed by Dr. Shani Saks, D.O. on Sept. 12, 2023 People with alopecia areata have gender-specific comorbidities, including anxiety, dermatitis, hypothyroidism, and hyperlipidemia. According to a recent study, interactions between gender, age, and the severity of the disease influence the onset of these associated diseases. Alopecia areata (AA) is a chronic inflammatory condition considered the second...